The effects of alcohol use severity and polygenic risk on gray matter volumes in young adults

The effects of alcohol use severity and polygenic risk on gray matter volumes in young adults

IntroductionGenetic factors contribute to alcohol misuse. Chronic alcohol consumption is associated with decreases in gray matter volumes (GMVs) of the brain. However, it remains unclear whether or how genetic risks may alter GMVs independent of the effects of alcohol exposure. MethodsHere, we emplo...

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Bibliographic Details
Main Authors: Yu Chen, Huey-Ting Li, Xingguang Luo, Guangfei Li, Jaime S. Ide, Chiang-Shan R. Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Psychiatry
Subjects:
HCP
alcohol dependence
polygenic risk score
VBM
thalamus
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1560053/full
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