Aging disrupts the link between network centrality and functional properties of prefrontal neurons during memory-guided behavior
Abstract The prefrontal cortex (PFC) is vital for higher cognitive functions and displays neuronal heterogeneity, with neuronal activity varying significantly across individual neurons. Using calcium imaging in the medial PFC (mPFC) of mice, we investigate whether differences in degree centrality—a...
Saved in:
| Main Authors: | Yadollah Ranjbar-Slamloo, Huee Ru Chong, Tsukasa Kamigaki |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07498-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Unraveling the roles of spatial working memory sustained and selective neurons in prefrontal cortex
by: Mohammad Aliramezani, et al.
Published: (2025-05-01) -
Prefrontal cortex neuronal ensembles dynamically encode task features during associative memory and virtual navigation
by: Mohamad Abbass, et al.
Published: (2025-01-01) -
Prefrontal cortex astrocytes modulate distinct neuronal populations to control anxiety-like behavior
by: Eunyoung Kim, et al.
Published: (2025-08-01) -
Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction
by: Yuki Mochizuki, et al.
Published: (2025-03-01) -
Medium Spiny Neurons Mediate Timing Perception in Coordination with Prefrontal Neurons in Primates
by: Xinhe Liu, et al.
Published: (2025-04-01)