Co-assembled Glycyrrhiza nanoparticles embedded supramolecular protein hydrogels to enhance licochalcone A release for acute inflammation management

Co-assembled Glycyrrhiza nanoparticles embedded supramolecular protein hydrogels to enhance licochalcone A release for acute inflammation management

Licochalcone A (LA) garnered remarkable acclaim in acute inflammation therapy, however, poor release capability from the matrix and oral bioavailability restrict its oral delivery. To address this challenge, licorice-derived glycyrrhizic acid (GA) and LA were co-assembled into GA-LA (GLA) binary co-...

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Bibliographic Details
Main Authors: Zhuxian Wang, Jun Liu, Yufan Wu, Yamei Li, Hongxia Zhu, Qiang Liu, Bin Yang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:International Journal of Pharmaceutics: X
Subjects:
Supramolecular hydrogels
Co-assembled natural products
Licochalcone a
Acute inflammation
Drug release
Bioavailability
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156725000283
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