Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients
Objective To investigate the influence of high flux hemodialysis（HFHD）on microinflam-matory and nutritional status of uremic patients. Methods 155 cases of uremic patients in our hospital from January 2013 to June 2015 were randomly divided into two groups: 82 cases of uremic patients with uremic tr...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2017-01-01
|
| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57916833&Fpath=home&index=0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850142862458486784 |
|---|---|
| author | LIU Na ZHOU Lu DING Kun CHEN Ren-gui ZHAO Wen-qi YE Ting SU Dong-dong |
| author_facet | LIU Na ZHOU Lu DING Kun CHEN Ren-gui ZHAO Wen-qi YE Ting SU Dong-dong |
| author_sort | LIU Na |
| collection | DOAJ |
| description | Objective To investigate the influence of high flux hemodialysis（HFHD）on microinflam-matory and nutritional status of uremic patients. Methods 155 cases of uremic patients in our hospital from January 2013 to June 2015 were randomly divided into two groups: 82 cases of uremic patients with uremic treated by HFHD were selected into observation group,and 73 cases of uremic patients with uremic treated by hemodiafiltration + hemoperfusion（ HDF + HP） in the same period were selected into control group.Before and 12 months after the treatment,blood samples of 155 patients in each group were taken to detect the indicators of hypersensitive C-reactive protein（ hs-CRP）,interleukin（ IL-6）,tumor necrosis factor（TNF-α）,triglycerides（ TC）,total cholesterol（ TC）,β<sub>2</sub>-microglobulin（ β<sub>2</sub>-MG）,serum creatinine（SCr）,serum phosphorus（Ph）,body mass index（BMI）,total protein（TP）,albumin（Alb）,and statistical analyzed. Results After treatment,hs-CRP、IL-6、TNF-α levels of two groups were significantly reduced,statistically difference（ P < 0. 05）,and hs-CRP、IL-6、TNF-α levels of observation group were significantly lower than control group,statistically difference（ P < 0. 05）. After treatment,TG,TC,β<sub>2</sub>-MG,SCr,Ph levels of two groups were significantly reduced,statistically difference（ P < 0. 05）,and TG,TC,β<sub>2</sub>-MG,Scr,Ph levels of observation group were significantly lower than control group,statistically difference（ P < 0. 05）. After BMI,TP,Alb levels of two groups were significantly increased,statistically difference（ P < 0. 05）,and BMI,TP,Alb levels of observation group were significantly higher than control group,statistically difference（ P < 0. 05）. Conclusions Compared with hemodiafiltration + hemoperfusion（HDF + HP）,high flux hemodialysis could effectively improve the microinflammatory,renal function and nutritional status of uremic patients. |
| format | Article |
| id | doaj-art-c59ad92495e54e02af9b4ca8a7e40b67 |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2017-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-c59ad92495e54e02af9b4ca8a7e40b672025-08-20T02:28:55ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902017-01-0166767057916833Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patientsLIU NaZHOU LuDING KunCHEN Ren-guiZHAO Wen-qiYE TingSU Dong-dongObjective To investigate the influence of high flux hemodialysis（HFHD）on microinflam-matory and nutritional status of uremic patients. Methods 155 cases of uremic patients in our hospital from January 2013 to June 2015 were randomly divided into two groups: 82 cases of uremic patients with uremic treated by HFHD were selected into observation group,and 73 cases of uremic patients with uremic treated by hemodiafiltration + hemoperfusion（ HDF + HP） in the same period were selected into control group.Before and 12 months after the treatment,blood samples of 155 patients in each group were taken to detect the indicators of hypersensitive C-reactive protein（ hs-CRP）,interleukin（ IL-6）,tumor necrosis factor（TNF-α）,triglycerides（ TC）,total cholesterol（ TC）,β<sub>2</sub>-microglobulin（ β<sub>2</sub>-MG）,serum creatinine（SCr）,serum phosphorus（Ph）,body mass index（BMI）,total protein（TP）,albumin（Alb）,and statistical analyzed. Results After treatment,hs-CRP、IL-6、TNF-α levels of two groups were significantly reduced,statistically difference（ P < 0. 05）,and hs-CRP、IL-6、TNF-α levels of observation group were significantly lower than control group,statistically difference（ P < 0. 05）. After treatment,TG,TC,β<sub>2</sub>-MG,SCr,Ph levels of two groups were significantly reduced,statistically difference（ P < 0. 05）,and TG,TC,β<sub>2</sub>-MG,Scr,Ph levels of observation group were significantly lower than control group,statistically difference（ P < 0. 05）. After BMI,TP,Alb levels of two groups were significantly increased,statistically difference（ P < 0. 05）,and BMI,TP,Alb levels of observation group were significantly higher than control group,statistically difference（ P < 0. 05）. Conclusions Compared with hemodiafiltration + hemoperfusion（HDF + HP）,high flux hemodialysis could effectively improve the microinflammatory,renal function and nutritional status of uremic patients.http://www.lcszb.com/thesisDetails?columnId=57916833&Fpath=home&index=0High flux hemodialysisHemodiafiltrationHemoper fusionUremiaMicroinflammatoryNutritional status |
| spellingShingle | LIU Na ZHOU Lu DING Kun CHEN Ren-gui ZHAO Wen-qi YE Ting SU Dong-dong Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients Linchuang shenzangbing zazhi High flux hemodialysis Hemodiafiltration Hemoper fusion Uremia Microinflammatory Nutritional status |
| title | Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients |
| title_full | Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients |
| title_fullStr | Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients |
| title_full_unstemmed | Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients |
| title_short | Influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients |
| title_sort | influence of high flux hemodialysis on microinflammatory and nutritional status of uremic patients |
| topic | High flux hemodialysis Hemodiafiltration Hemoper fusion Uremia Microinflammatory Nutritional status |
| url | http://www.lcszb.com/thesisDetails?columnId=57916833&Fpath=home&index=0 |
| work_keys_str_mv | AT liuna influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients AT zhoulu influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients AT dingkun influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients AT chenrengui influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients AT zhaowenqi influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients AT yeting influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients AT sudongdong influenceofhighfluxhemodialysisonmicroinflammatoryandnutritionalstatusofuremicpatients |