Recent advances in T-cell receptor repertoire analysis: Bridging the gap with multimodal single-cell RNA sequencing

T cells exercise a multitude of functions such as cytotoxicity, secretion of immunomodulating cytokines or regulation of tolerance, collectively resulting in an effective control of immune-related disease. Through the unique mechanism of V(D)J recombination, T cells express a highly specific recepto...

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Bibliographic Details
Main Authors: Sebastiaan Valkiers, Nicky de Vrij, Sofie Gielis, Sara Verbandt, Benson Ogunjimi, Kris Laukens, Pieter Meysman
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:ImmunoInformatics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667119022000015
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