Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution

One of the most significant risk factors for the formation  of internal  genital organs is connective  tissue diseases. The steady increase in the number of women suffering from pelvic organ prolapse has led to the fact that this pathology has become both a medical and socio-economic problem in many...

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Main Authors: M. S. Selikhova, V. V. Skvortsov, G. V. Ershov, A. G. Ershov, G. I. Malyakin
Format: Article
Language:Russian
Published: Open Systems Publication 2022-01-01
Series:Лечащий Врач
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Online Access:https://journal.lvrach.ru/jour/article/view/855
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author M. S. Selikhova
V. V. Skvortsov
G. V. Ershov
A. G. Ershov
G. I. Malyakin
author_facet M. S. Selikhova
V. V. Skvortsov
G. V. Ershov
A. G. Ershov
G. I. Malyakin
author_sort M. S. Selikhova
collection DOAJ
description One of the most significant risk factors for the formation  of internal  genital organs is connective  tissue diseases. The steady increase in the number of women suffering from pelvic organ prolapse has led to the fact that this pathology has become both a medical and socio-economic problem in many countries. At the same time, the data on the role of undifferentiated connective tissue dysplasias in the development of pelvic organ prolapse and in the formation of pelvic floor insufficiency and the possibility of using it to predict this pathology are contradictory.  To determine the relationship between the manifestation of undifferentiated connective tissue dysplasia and the development of pelvic organ prolapse, a retrospective analysis of 157 case histories of patients with genital prolapse was carried out. In 27,39% of patients, manifestations of connective tissue dysplasia were noted. In 39,53% of cases, a combination of the manifestation of undifferentiated  connective tissue dysplasias with birth traumatism was revealed. Severe forms of connective tissue dysplasia (varicose veins of the lower extremities, intestinal polyposis, mitral valve prolapse) were found in 16,28% of the number of cases with birth traumatism and pelvic organ prolapse, which required surgical correction  before pregnancy or after childbirth. Revealed in every third patient operated on for pelvic floor incompetence, undifferentiated connective tissue dysplasias allows us to consider it as a risk factor for pelvic organ prolapse, especially in combination with perineal trauma during childbirth. However, to assess the role and significance of connective tissue pathology in predicting the formation of prolapse and prolapse of the internal genital organs of the small pelvis in a woman, prospective randomized  studies are needed.
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spelling doaj-art-c592a5b6fbd241f9ba7a09e20ee12cec2025-08-20T03:20:16ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812022-01-01012222510.51793/OS.2021.24.12.003850Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolutionM. S. Selikhova0V. V. Skvortsov1G. V. Ershov2A. G. Ershov3G. I. Malyakin4Volgograd State Medical University of the Ministry of Health of the Russian FederationVolgograd State Medical University of the Ministry of Health of the Russian FederationPrivate Founding of Health Service Clinical Hospital Russian Railroads – Medicine VolgdgradVolgograd State Medical University of the Ministry of Health of the Russian FederationVolgograd State Medical University of the Ministry of Health of the Russian FederationOne of the most significant risk factors for the formation  of internal  genital organs is connective  tissue diseases. The steady increase in the number of women suffering from pelvic organ prolapse has led to the fact that this pathology has become both a medical and socio-economic problem in many countries. At the same time, the data on the role of undifferentiated connective tissue dysplasias in the development of pelvic organ prolapse and in the formation of pelvic floor insufficiency and the possibility of using it to predict this pathology are contradictory.  To determine the relationship between the manifestation of undifferentiated connective tissue dysplasia and the development of pelvic organ prolapse, a retrospective analysis of 157 case histories of patients with genital prolapse was carried out. In 27,39% of patients, manifestations of connective tissue dysplasia were noted. In 39,53% of cases, a combination of the manifestation of undifferentiated  connective tissue dysplasias with birth traumatism was revealed. Severe forms of connective tissue dysplasia (varicose veins of the lower extremities, intestinal polyposis, mitral valve prolapse) were found in 16,28% of the number of cases with birth traumatism and pelvic organ prolapse, which required surgical correction  before pregnancy or after childbirth. Revealed in every third patient operated on for pelvic floor incompetence, undifferentiated connective tissue dysplasias allows us to consider it as a risk factor for pelvic organ prolapse, especially in combination with perineal trauma during childbirth. However, to assess the role and significance of connective tissue pathology in predicting the formation of prolapse and prolapse of the internal genital organs of the small pelvis in a woman, prospective randomized  studies are needed.https://journal.lvrach.ru/jour/article/view/855genital prolapseconnective tissue dysplasiarisk factorssocial-active agesurgical treatment
spellingShingle M. S. Selikhova
V. V. Skvortsov
G. V. Ershov
A. G. Ershov
G. I. Malyakin
Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
Лечащий Врач
genital prolapse
connective tissue dysplasia
risk factors
social-active age
surgical treatment
title Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
title_full Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
title_fullStr Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
title_full_unstemmed Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
title_short Support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
title_sort support role undifferentiated connective tissue dysplasia in genital organ rolapse evolution
topic genital prolapse
connective tissue dysplasia
risk factors
social-active age
surgical treatment
url https://journal.lvrach.ru/jour/article/view/855
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AT vvskvortsov supportroleundifferentiatedconnectivetissuedysplasiaingenitalorganrolapseevolution
AT gvershov supportroleundifferentiatedconnectivetissuedysplasiaingenitalorganrolapseevolution
AT agershov supportroleundifferentiatedconnectivetissuedysplasiaingenitalorganrolapseevolution
AT gimalyakin supportroleundifferentiatedconnectivetissuedysplasiaingenitalorganrolapseevolution