Phage-antibiotic synergy to combat multidrug resistant strains of Gram-negative ESKAPE pathogens

Phage-antibiotic synergy to combat multidrug resistant strains of Gram-negative ESKAPE pathogens

Abstract Bacteriophage-antibiotic-synergy (PAS) was investigated to target Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii and Enterobacter cloacae. Whole genome sequencing indicated that bacteriophage KPW17 targeting K. pneumoniae, clustered with genus Webervirus, ECSR5 targe...

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Bibliographic Details
Main Authors: Tinta Carmen Morris, Brandon Reyneke, Sehaam Khan, Wesaal Khan
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Bacteriophages
Antibiotics
Pathogens
Synergy
ESKAPE
Combination therapies
Online Access:https://doi.org/10.1038/s41598-025-01489-y
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