Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass
Microbial decomposition of persistent natural compounds such as phenolic lignin and polysaccharides in plant cell walls plays a crucial role in the global carbon cycle and underpins diverse biotechnological applications. Among microbial decomposers, fungi from the <i>Ascomycota</i> and &...
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MDPI AG
2025-06-01
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| author | Rafael Icaro Matos Vieira Alencar da Silva Peixoto Antonielle Vieira Monclaro Carlos André Ornelas Ricart Edivaldo Ximenes Ferreira Filho Robert Neil Gerard Miller Taísa Godoy Gomes |
| author_facet | Rafael Icaro Matos Vieira Alencar da Silva Peixoto Antonielle Vieira Monclaro Carlos André Ornelas Ricart Edivaldo Ximenes Ferreira Filho Robert Neil Gerard Miller Taísa Godoy Gomes |
| author_sort | Rafael Icaro Matos Vieira |
| collection | DOAJ |
| description | Microbial decomposition of persistent natural compounds such as phenolic lignin and polysaccharides in plant cell walls plays a crucial role in the global carbon cycle and underpins diverse biotechnological applications. Among microbial decomposers, fungi from the <i>Ascomycota</i> and <i>Basidiomycota</i> phyla have evolved specialized mechanisms for efficient lignocellulosic biomass degradation, employing extracellular enzymes and synergistic fungal consortia. Fungal coculture, defined as the controlled, axenic cultivation of multiple fungal species or strains in a single culture medium, is a promising strategy for industrial processes. This approach to biomass conversion offers potential for enhancing production of enzymes, biofuels, and other high-value bioproducts, while enabling investigation of ecological dynamics and metabolic pathways relevant to biorefinery operations. Lignocellulosic biomass conversion into fuels, energy, and biochemicals is central to the bioeconomy, integrating advanced biotechnology with sustainable resource use. Recent advancements in -omics technologies, including genomics, transcriptomics, and proteomics, have facilitated detailed analysis of fungal metabolism, uncovering novel secondary metabolites and enzymatic pathways activated under specific growth conditions. This review highlights the potential of fungal coculture systems to advance sustainable biomass conversion in alignment with circular bioeconomy goals. |
| format | Article |
| id | doaj-art-c586f33a8fb644c58fed4f0d28d040a8 |
| institution | Kabale University |
| issn | 2309-608X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj-art-c586f33a8fb644c58fed4f0d28d040a82025-08-20T03:27:22ZengMDPI AGJournal of Fungi2309-608X2025-06-0111645810.3390/jof11060458Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic BiomassRafael Icaro Matos Vieira0Alencar da Silva Peixoto1Antonielle Vieira Monclaro2Carlos André Ornelas Ricart3Edivaldo Ximenes Ferreira Filho4Robert Neil Gerard Miller5Taísa Godoy Gomes6Laboratory of Microbiology, Department of Cell Biology, University of Brasília, Brasilia 70910-900, DF, BrazilLaboratory of Microbiology, Department of Cell Biology, University of Brasília, Brasilia 70910-900, DF, BrazilCenter for Microbial Ecology and Technology (CMET), Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, BelgiumLaboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, University of Brasília, Brasilia 70910-900, DF, BrazilLaboratory of Enzymology, Department of Cell Biology, University of Brasília, Brasilia 70910-900, DF, BrazilLaboratory of Microbiology, Department of Cell Biology, University of Brasília, Brasilia 70910-900, DF, BrazilLaboratory of Microbiology, Department of Cell Biology, University of Brasília, Brasilia 70910-900, DF, BrazilMicrobial decomposition of persistent natural compounds such as phenolic lignin and polysaccharides in plant cell walls plays a crucial role in the global carbon cycle and underpins diverse biotechnological applications. Among microbial decomposers, fungi from the <i>Ascomycota</i> and <i>Basidiomycota</i> phyla have evolved specialized mechanisms for efficient lignocellulosic biomass degradation, employing extracellular enzymes and synergistic fungal consortia. Fungal coculture, defined as the controlled, axenic cultivation of multiple fungal species or strains in a single culture medium, is a promising strategy for industrial processes. This approach to biomass conversion offers potential for enhancing production of enzymes, biofuels, and other high-value bioproducts, while enabling investigation of ecological dynamics and metabolic pathways relevant to biorefinery operations. Lignocellulosic biomass conversion into fuels, energy, and biochemicals is central to the bioeconomy, integrating advanced biotechnology with sustainable resource use. Recent advancements in -omics technologies, including genomics, transcriptomics, and proteomics, have facilitated detailed analysis of fungal metabolism, uncovering novel secondary metabolites and enzymatic pathways activated under specific growth conditions. This review highlights the potential of fungal coculture systems to advance sustainable biomass conversion in alignment with circular bioeconomy goals.https://www.mdpi.com/2309-608X/11/6/458cocultureenzyme productionCAZYmesmetabolitesomics technologies |
| spellingShingle | Rafael Icaro Matos Vieira Alencar da Silva Peixoto Antonielle Vieira Monclaro Carlos André Ornelas Ricart Edivaldo Ximenes Ferreira Filho Robert Neil Gerard Miller Taísa Godoy Gomes Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass Journal of Fungi coculture enzyme production CAZYmes metabolites omics technologies |
| title | Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass |
| title_full | Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass |
| title_fullStr | Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass |
| title_full_unstemmed | Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass |
| title_short | Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass |
| title_sort | fungal coculture unlocking the potential for efficient bioconversion of lignocellulosic biomass |
| topic | coculture enzyme production CAZYmes metabolites omics technologies |
| url | https://www.mdpi.com/2309-608X/11/6/458 |
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