Enhanced Brain Tumor Classification Using MobileNetV2: A Comprehensive Preprocessing and Fine-Tuning Approach

<b>Background:</b> Brain tumors are among the most difficult diseases to deal with in modern medicine due to the uncontrolled cell proliferation, which causes grave damage to the nervous system. Brain tumors can be broadly classified into two categories: primary tumors, which originate w...

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Bibliographic Details
Main Authors: Md Atiqur Rahman, Mohammad Badrul Alam Miah, Md. Abir Hossain, A. S. M. Sanwar Hosen
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:BioMedInformatics
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Online Access:https://www.mdpi.com/2673-7426/5/2/30
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Summary:<b>Background:</b> Brain tumors are among the most difficult diseases to deal with in modern medicine due to the uncontrolled cell proliferation, which causes grave damage to the nervous system. Brain tumors can be broadly classified into two categories: primary tumors, which originate within the brain, and secondary tumors, which are metastatic in nature. Effective glioma, meningioma, and pituitary tumor diagnosis and treatment requires the precise differentiation of these tumors as well as non-tumors for improved clinical outcomes. <b>Methods:</b> Here, we present a new method to classify brain tumors based on the MobileNetV2 architecture with advanced preprocessing for high accuracy. We accessed an MRI image dataset from Kaggle that contained 1311 images in the test set. We split the data into 80% training and 20% testing. All images underwent extensive preprocessing, including grayscale conversion, noise removal, and contrast-limited-adaptive-histogram equalization (CLAHE). All images were resized to 224 × 224 pixels. Using transfer learning, the baseline frozen layers were kept intact while the top layers were trained with a learning rate of 0.0001, which was tuned to the model’s requirements using early stopping to avoid overfitting. <b>Results:</b> With the outlined methodology, we obtained an astounding accuracy of 99.16%, including strong performance in the no-tumor category, where recall rates were approaching 100% and false positive rates were minimized. <b>Conclusions:</b> These findings strongly indicate that the application of lightweight convolutional neural networks in diagnostic imaging can considerably expedite accurate brain tumor identification by radiologists.
ISSN:2673-7426