Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19

Introduction: Coronavirus disease 19 (COVID-19) has been a global public health emergency, with 209.89 million cases of infection with SARS-CoV-2 recorded, resulting in 4,401,675 deaths. After recuperation, it is probable that COVID-19 patients have sequelae of the disease. This study aimed to eval...

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Main Authors: Margarita de la Luz Martinez-Fierro, Jose Isaias Badillo-Almaraz, Jose Ramon Muñoz-Torres, Griselda Aide Cabral Pacheco, Idalia Garza-Veloz, Edgar Fernando Gutierrez-Vela, Lucia Socorro Hernandez-Marquez, Lizbeth Areli Hernandez-Marquez, Alondra Daniela Torres-Gaytan, Juan Carlos Alvarez-Castro, Claudia Caldera-Villalobos, Ivan Delgado-Enciso, Iram Pablo Rodriguez-Sanchez, Oscar Gustavo Meza-Zavala, Yolanda Ortiz-Castro
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2022-01-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/13772
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author Margarita de la Luz Martinez-Fierro
Jose Isaias Badillo-Almaraz
Jose Ramon Muñoz-Torres
Griselda Aide Cabral Pacheco
Idalia Garza-Veloz
Edgar Fernando Gutierrez-Vela
Lucia Socorro Hernandez-Marquez
Lizbeth Areli Hernandez-Marquez
Alondra Daniela Torres-Gaytan
Juan Carlos Alvarez-Castro
Claudia Caldera-Villalobos
Ivan Delgado-Enciso
Iram Pablo Rodriguez-Sanchez
Oscar Gustavo Meza-Zavala
Yolanda Ortiz-Castro
author_facet Margarita de la Luz Martinez-Fierro
Jose Isaias Badillo-Almaraz
Jose Ramon Muñoz-Torres
Griselda Aide Cabral Pacheco
Idalia Garza-Veloz
Edgar Fernando Gutierrez-Vela
Lucia Socorro Hernandez-Marquez
Lizbeth Areli Hernandez-Marquez
Alondra Daniela Torres-Gaytan
Juan Carlos Alvarez-Castro
Claudia Caldera-Villalobos
Ivan Delgado-Enciso
Iram Pablo Rodriguez-Sanchez
Oscar Gustavo Meza-Zavala
Yolanda Ortiz-Castro
author_sort Margarita de la Luz Martinez-Fierro
collection DOAJ
description Introduction: Coronavirus disease 19 (COVID-19) has been a global public health emergency, with 209.89 million cases of infection with SARS-CoV-2 recorded, resulting in 4,401,675 deaths. After recuperation, it is probable that COVID-19 patients have sequelae of the disease. This study aimed to evaluate the respiratory anatomical–functional sequelae in Mexican patients who recovered from COVID-19. Methodology: This study included twenty-four patients who recovered from COVID-19 and eight non-infected patients (controls). Participants were screened for SARS-CoV-2 and the presence of IgM/IgG antibodies. Pulmonary function and lung anatomical abnormalities were evaluated by spirometry and computerized tomography. Results: A total of 45.8% of the patients had pulmonary function with obstructive patterns: 70.8% of recovered cases had COVID-19 Reporting and Data System (CO-RADS) 1, 20.8% CO-RADS 3 and 16.7% CO-RADS 4. A total of 35.3% of patients with CO-RADS 1 also showed bilateral nodal growth; 70.8% of patients tested positive for IgG and 8.4% for IgG/IgM, and 20.8% tested negative for both antibodies. Conclusions: There were respiratory anatomical and functional sequelae in Mexican patients who recovered from COVID-19, with a high occurrence of pulmonary obstructive patterns in the study population. These observations indicate the importance of the routine evaluation of sequelae in Mexican patients who recovered from COVID-19 and the need for strict follow-up to improve the quality of life of these patients.
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spelling doaj-art-c57c232696a84bc4a88fc0906f814ecd2025-08-20T02:57:01ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802022-01-01160110.3855/jidc.13772Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19Margarita de la Luz Martinez-Fierro0Jose Isaias Badillo-Almaraz1Jose Ramon Muñoz-Torres2Griselda Aide Cabral Pacheco3Idalia Garza-Veloz4Edgar Fernando Gutierrez-Vela5Lucia Socorro Hernandez-Marquez6Lizbeth Areli Hernandez-Marquez7Alondra Daniela Torres-Gaytan8Juan Carlos Alvarez-Castro9Claudia Caldera-Villalobos10Ivan Delgado-Enciso11Iram Pablo Rodriguez-Sanchez12Oscar Gustavo Meza-Zavala13Yolanda Ortiz-Castro14Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoGeneral Hospital of Zacatecas "Luz González Cosío", Zacatecas Health Services, Zacatecas, MéxicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoDepartment of Molecular Medicine, School of Medicine, University of Colima, Colima, MexicoMolecular and Structural Physiology Laboratory, School of Biological Sciences, Autonomous University of Nuevo León, Monterrey, Nuevo León, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas, Mexico Introduction: Coronavirus disease 19 (COVID-19) has been a global public health emergency, with 209.89 million cases of infection with SARS-CoV-2 recorded, resulting in 4,401,675 deaths. After recuperation, it is probable that COVID-19 patients have sequelae of the disease. This study aimed to evaluate the respiratory anatomical–functional sequelae in Mexican patients who recovered from COVID-19. Methodology: This study included twenty-four patients who recovered from COVID-19 and eight non-infected patients (controls). Participants were screened for SARS-CoV-2 and the presence of IgM/IgG antibodies. Pulmonary function and lung anatomical abnormalities were evaluated by spirometry and computerized tomography. Results: A total of 45.8% of the patients had pulmonary function with obstructive patterns: 70.8% of recovered cases had COVID-19 Reporting and Data System (CO-RADS) 1, 20.8% CO-RADS 3 and 16.7% CO-RADS 4. A total of 35.3% of patients with CO-RADS 1 also showed bilateral nodal growth; 70.8% of patients tested positive for IgG and 8.4% for IgG/IgM, and 20.8% tested negative for both antibodies. Conclusions: There were respiratory anatomical and functional sequelae in Mexican patients who recovered from COVID-19, with a high occurrence of pulmonary obstructive patterns in the study population. These observations indicate the importance of the routine evaluation of sequelae in Mexican patients who recovered from COVID-19 and the need for strict follow-up to improve the quality of life of these patients. https://jidc.org/index.php/journal/article/view/13772pulmonary sequelaeSARS-CoV-2COVID-19coronaviruscomputerized tomography scan
spellingShingle Margarita de la Luz Martinez-Fierro
Jose Isaias Badillo-Almaraz
Jose Ramon Muñoz-Torres
Griselda Aide Cabral Pacheco
Idalia Garza-Veloz
Edgar Fernando Gutierrez-Vela
Lucia Socorro Hernandez-Marquez
Lizbeth Areli Hernandez-Marquez
Alondra Daniela Torres-Gaytan
Juan Carlos Alvarez-Castro
Claudia Caldera-Villalobos
Ivan Delgado-Enciso
Iram Pablo Rodriguez-Sanchez
Oscar Gustavo Meza-Zavala
Yolanda Ortiz-Castro
Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
Journal of Infection in Developing Countries
pulmonary sequelae
SARS-CoV-2
COVID-19
coronavirus
computerized tomography scan
title Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
title_full Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
title_fullStr Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
title_full_unstemmed Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
title_short Evaluation of respiratory anatomical-functional sequelae in patients who recovered from COVID-19
title_sort evaluation of respiratory anatomical functional sequelae in patients who recovered from covid 19
topic pulmonary sequelae
SARS-CoV-2
COVID-19
coronavirus
computerized tomography scan
url https://jidc.org/index.php/journal/article/view/13772
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