Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants
A 71-year-old man with known history of atrial fibrillation (treated with routine rivaroxaban therapy) was found to have incidental biochemical elevated calcium and parathyroid hormone (PTH) levels. His physical examination demonstrated the presence of a palpable right neck mass. Subsequent imaging...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2018/9261749 |
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| author | Raoul Verzijl Pim J. Bongers Geetha Mukerji Ozgur Mete Karen M. Devon Jesse D. Pasternak |
| author_facet | Raoul Verzijl Pim J. Bongers Geetha Mukerji Ozgur Mete Karen M. Devon Jesse D. Pasternak |
| author_sort | Raoul Verzijl |
| collection | DOAJ |
| description | A 71-year-old man with known history of atrial fibrillation (treated with routine rivaroxaban therapy) was found to have incidental biochemical elevated calcium and parathyroid hormone (PTH) levels. His physical examination demonstrated the presence of a palpable right neck mass. Subsequent imaging studies revealed a large parathyroid mass as well as multiple bone lesions, raising the suspicion of parathyroid carcinoma. The anticoagulant therapy was stopped 5 days prior to his elective surgery. The night before his elective surgery, he presented to the emergency room with profound hypocalcemia. The surgery was postponed and rescheduled after calcium correction. Intraoperative findings and detailed histopathological examination revealed an infarcted 4.0 cm parathyroid adenoma with cystic change. His bony changes were related to brown tumors associated with long-standing hyperparathyroidism. Autoinfarction of a large parathyroid adenoma causing severe hypocalcemia is a rare phenomenon and may be considered in patients with large parathyroid adenomas after withdrawal of anticoagulants. |
| format | Article |
| id | doaj-art-c579232475c54a55a68b665490156479 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-c579232475c54a55a68b6654901564792025-02-03T05:58:18ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/92617499261749Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of AnticoagulantsRaoul Verzijl0Pim J. Bongers1Geetha Mukerji2Ozgur Mete3Karen M. Devon4Jesse D. Pasternak5Division of General Surgery, Department of Surgery, University Health Network, CanadaDivision of General Surgery, Department of Surgery, University Health Network, CanadaDivision of Endocrinology, Department of Medicine, Women’s College Hospital, CanadaDepartment of Pathology, University Health Network, CanadaDivision of General Surgery, Department of Surgery, University Health Network, CanadaDivision of General Surgery, Department of Surgery, University Health Network, CanadaA 71-year-old man with known history of atrial fibrillation (treated with routine rivaroxaban therapy) was found to have incidental biochemical elevated calcium and parathyroid hormone (PTH) levels. His physical examination demonstrated the presence of a palpable right neck mass. Subsequent imaging studies revealed a large parathyroid mass as well as multiple bone lesions, raising the suspicion of parathyroid carcinoma. The anticoagulant therapy was stopped 5 days prior to his elective surgery. The night before his elective surgery, he presented to the emergency room with profound hypocalcemia. The surgery was postponed and rescheduled after calcium correction. Intraoperative findings and detailed histopathological examination revealed an infarcted 4.0 cm parathyroid adenoma with cystic change. His bony changes were related to brown tumors associated with long-standing hyperparathyroidism. Autoinfarction of a large parathyroid adenoma causing severe hypocalcemia is a rare phenomenon and may be considered in patients with large parathyroid adenomas after withdrawal of anticoagulants.http://dx.doi.org/10.1155/2018/9261749 |
| spellingShingle | Raoul Verzijl Pim J. Bongers Geetha Mukerji Ozgur Mete Karen M. Devon Jesse D. Pasternak Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants Case Reports in Surgery |
| title | Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants |
| title_full | Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants |
| title_fullStr | Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants |
| title_full_unstemmed | Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants |
| title_short | Autoinfarction of Giant Parathyroid Adenoma after Preoperative Withdrawal of Anticoagulants |
| title_sort | autoinfarction of giant parathyroid adenoma after preoperative withdrawal of anticoagulants |
| url | http://dx.doi.org/10.1155/2018/9261749 |
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