Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

The members of the Mycobacterium tuberculosis complex (MTBC) causing human tuberculosis comprise 10 phylogenetic lineages that differ in their geographical distribution. The human consequences of this phylogenetic diversity remain poorly understood. Here, we assessed the phenotypic properties at the...

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Bibliographic Details
Main Authors:	Ainhoa Arbués, Sarah Schmidiger, Miriam Reinhard, Sonia Borrell, Sebastien Gagneux, Damien Portevin
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2025-03-01
Series:	eLife
Subjects:	Mycobacterium tuberculosis complex tuberculosis lineage granuloma host-pathogen interaction virulence
Online Access:	https://elifesciences.org/articles/99062
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