Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace
BackgroundIn the combination antiretroviral therapy era, HIV-associated neurocognitive disorder (HAND) is still widespread among HIV-infected individuals. However, there is no effective treatment for HAND, and the exact pathogenic mechanism of HAND remains unknown. This paper aims to provide a refer...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1478187/full |
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| author | Tingting Zhou Xuannan Chen Yu Lai |
| author_facet | Tingting Zhou Xuannan Chen Yu Lai |
| author_sort | Tingting Zhou |
| collection | DOAJ |
| description | BackgroundIn the combination antiretroviral therapy era, HIV-associated neurocognitive disorder (HAND) is still widespread among HIV-infected individuals. However, there is no effective treatment for HAND, and the exact pathogenic mechanism of HAND remains unknown. This paper aims to provide a reference for further exploration in the field of HAND research.MethodsWe used CiteSpace software to collect 3057 articles related to HAND in the Web of Science Core Collection for comprehensive analysis. Betweenness centrality, count, and burst values were used as indicators in the visualization analysis, aiming to predict future new directions and cutting-edge trends.ResultsThe last decade has been the peak period of HAND research, with the most prominent contributions by authors, countries, and institutions being Grant, Igor (135), the USA (2211), and the University of California System (758), respectively. The most frequently cited article is “HIV-associated neurocognitive disorders persist in the area of potent antiretroviral therapy: CHARTER Study.” The hotspots in this field are “neurocognitive impairment,” “central nervous system,” “cerebrospinal fluid,” “HIV-1 tat,” “SIV,” “inflammation,” “infection,” and “pathogenesis.” The current research direction of HAND is focused on exploring the pathogenic mechanism underlying HIV-associated neurocognitive impairment and potential therapeutic targets.ConclusionThis study provides a bibliometric visualization of HAND-related literature to gain insight into the development and frontiers of this research field. The study also provides scholars with detailed references and identifies future research directions to better promote the development of this field of research. |
| format | Article |
| id | doaj-art-c564944401fa419696cacae790289ffe |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-c564944401fa419696cacae790289ffe2025-02-03T06:33:39ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-02-011610.3389/fimmu.2025.14781871478187Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpaceTingting Zhou0Xuannan Chen1Yu Lai2School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupunture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaBackgroundIn the combination antiretroviral therapy era, HIV-associated neurocognitive disorder (HAND) is still widespread among HIV-infected individuals. However, there is no effective treatment for HAND, and the exact pathogenic mechanism of HAND remains unknown. This paper aims to provide a reference for further exploration in the field of HAND research.MethodsWe used CiteSpace software to collect 3057 articles related to HAND in the Web of Science Core Collection for comprehensive analysis. Betweenness centrality, count, and burst values were used as indicators in the visualization analysis, aiming to predict future new directions and cutting-edge trends.ResultsThe last decade has been the peak period of HAND research, with the most prominent contributions by authors, countries, and institutions being Grant, Igor (135), the USA (2211), and the University of California System (758), respectively. The most frequently cited article is “HIV-associated neurocognitive disorders persist in the area of potent antiretroviral therapy: CHARTER Study.” The hotspots in this field are “neurocognitive impairment,” “central nervous system,” “cerebrospinal fluid,” “HIV-1 tat,” “SIV,” “inflammation,” “infection,” and “pathogenesis.” The current research direction of HAND is focused on exploring the pathogenic mechanism underlying HIV-associated neurocognitive impairment and potential therapeutic targets.ConclusionThis study provides a bibliometric visualization of HAND-related literature to gain insight into the development and frontiers of this research field. The study also provides scholars with detailed references and identifies future research directions to better promote the development of this field of research.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1478187/fullHIVAIDSHIV-associated neurocognitive disorderneurocognitive impairmentCiteSpacebibliometric analysisvisualized analysis |
| spellingShingle | Tingting Zhou Xuannan Chen Yu Lai Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace Frontiers in Immunology HIVAIDS HIV-associated neurocognitive disorder neurocognitive impairment CiteSpace bibliometric analysis visualized analysis |
| title | Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace |
| title_full | Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace |
| title_fullStr | Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace |
| title_full_unstemmed | Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace |
| title_short | Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace |
| title_sort | development of research on hiv associated neurocognitive disorder and emerging trends a visualization analysis via citespace |
| topic | HIVAIDS HIV-associated neurocognitive disorder neurocognitive impairment CiteSpace bibliometric analysis visualized analysis |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1478187/full |
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