Management of Chondrosarcoma of the Mandible
Aim: The aim of this study is to present the clinicopathological characteristics of chondrosarcoma of the mandible. Material and Method: This retrospective study included patients diagnosed with chondrosarcoma of the mandible who underwent tumor excision with subsequent reconstruction. Results:...
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| Format: | Article |
| Language: | English |
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The Association of Otolaryngologists of India, West Bengal
2025-08-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
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| Online Access: | https://bjohns.in/journal23/index.php/bjohns/article/view/128 |
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| author | KRISHNAPPA R RAHUL SHAH ARSHAD ALI JAYKUMAR PATEL |
| author_facet | KRISHNAPPA R RAHUL SHAH ARSHAD ALI JAYKUMAR PATEL |
| author_sort | KRISHNAPPA R |
| collection | DOAJ |
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Aim: The aim of this study is to present the clinicopathological characteristics of chondrosarcoma of the mandible.
Material and Method: This retrospective study included patients diagnosed with chondrosarcoma of the mandible who underwent tumor excision with subsequent reconstruction.
Results: Three female patients, with a median age of 35 years, underwent wide local excision of mandibular chondrosarcoma followed by reconstruction. All patients presented with rapidly progressing painless facial swelling, and biopsy revealed neoplasms arranged in lobules composed of spindle cells exhibiting moderate cytoplasm, pleomorphic vesicular nuclei, and prominent nucleoli demonstrating moderate nuclear atypia. Central chondroid matrix containing atypical chondrocytes in lacunae was observed, along with a mitotic rate of 7-8/10 hpf, areas of necrosis, calcification, and Ki-67 positivity. Wide local excision of the primary tumor was performed in all cases, and none of the patients received radiotherapy. All patients were followed for at least one year, with no recurrence observed.
Conclusion: Early detection followed by radical surgical resection remains pivotal for achieving a favorable prognosis in mandibular chondrosarcoma. Given the high risk of recurrence, diligent long-term follow-up is imperative.
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| format | Article |
| id | doaj-art-c55d897cd1d14701948f2fe069b40e79 |
| institution | Kabale University |
| issn | 2395-2393 2395-2407 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj-art-c55d897cd1d14701948f2fe069b40e792025-08-26T08:45:22ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-23932395-24072025-08-0132310.47210/bjohns.2024.v32i3.128Management of Chondrosarcoma of the MandibleKRISHNAPPA R0RAHUL SHAH1ARSHAD ALI2JAYKUMAR PATEL3Kidwai Memorial Institute of Oncology, Dr. M. H. Marigowda Road, Bengaluru - 560029 The Gujarat Cancer & Research Institute, Civil Hospital Campus, Asarwa, Ahmedabad-380016. Gujarat, INDIAKidwai Memorial Institute of Oncology, Dr. M. H. Marigowda Road, Bengaluru - 560029Kidwai Memorial Institute of Oncology, Dr. M. H. Marigowda Road, Bengaluru - 560029 Aim: The aim of this study is to present the clinicopathological characteristics of chondrosarcoma of the mandible. Material and Method: This retrospective study included patients diagnosed with chondrosarcoma of the mandible who underwent tumor excision with subsequent reconstruction. Results: Three female patients, with a median age of 35 years, underwent wide local excision of mandibular chondrosarcoma followed by reconstruction. All patients presented with rapidly progressing painless facial swelling, and biopsy revealed neoplasms arranged in lobules composed of spindle cells exhibiting moderate cytoplasm, pleomorphic vesicular nuclei, and prominent nucleoli demonstrating moderate nuclear atypia. Central chondroid matrix containing atypical chondrocytes in lacunae was observed, along with a mitotic rate of 7-8/10 hpf, areas of necrosis, calcification, and Ki-67 positivity. Wide local excision of the primary tumor was performed in all cases, and none of the patients received radiotherapy. All patients were followed for at least one year, with no recurrence observed. Conclusion: Early detection followed by radical surgical resection remains pivotal for achieving a favorable prognosis in mandibular chondrosarcoma. Given the high risk of recurrence, diligent long-term follow-up is imperative. https://bjohns.in/journal23/index.php/bjohns/article/view/128Chondrosarcoma of mandible, Head and neck chondrosarcoma, Management of chondrosarcoma, Oral chondrosarcoma. |
| spellingShingle | KRISHNAPPA R RAHUL SHAH ARSHAD ALI JAYKUMAR PATEL Management of Chondrosarcoma of the Mandible Bengal Journal of Otolaryngology and Head Neck Surgery Chondrosarcoma of mandible, Head and neck chondrosarcoma, Management of chondrosarcoma, Oral chondrosarcoma. |
| title | Management of Chondrosarcoma of the Mandible |
| title_full | Management of Chondrosarcoma of the Mandible |
| title_fullStr | Management of Chondrosarcoma of the Mandible |
| title_full_unstemmed | Management of Chondrosarcoma of the Mandible |
| title_short | Management of Chondrosarcoma of the Mandible |
| title_sort | management of chondrosarcoma of the mandible |
| topic | Chondrosarcoma of mandible, Head and neck chondrosarcoma, Management of chondrosarcoma, Oral chondrosarcoma. |
| url | https://bjohns.in/journal23/index.php/bjohns/article/view/128 |
| work_keys_str_mv | AT krishnappar managementofchondrosarcomaofthemandible AT rahulshah managementofchondrosarcomaofthemandible AT arshadali managementofchondrosarcomaofthemandible AT jaykumarpatel managementofchondrosarcomaofthemandible |