Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient
Invasive aspergillosis represents a clinical picture frequently associated with host’s immunosuppression which usually involves a high morbidity and mortality. In general, the most frequent fungal entry is the lungs with secondary hematogenous dissemination, but there are other hypotheses like a gas...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2020/3601423 |
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| author | S. Guglielmetti C. M. Jaccard K. Mühlethaler A. Bigler D. Springe L. Ebnöther M. Delgado |
| author_facet | S. Guglielmetti C. M. Jaccard K. Mühlethaler A. Bigler D. Springe L. Ebnöther M. Delgado |
| author_sort | S. Guglielmetti |
| collection | DOAJ |
| description | Invasive aspergillosis represents a clinical picture frequently associated with host’s immunosuppression which usually involves a high morbidity and mortality. In general, the most frequent fungal entry is the lungs with secondary hematogenous dissemination, but there are other hypotheses like a gastrointestinal portal of entry. There are some rare publications of cases with invasive aspergillosis in immunocompetent patients. We present the case of an immunocompetent patient without any risk factors except for age, ICU stay, and surgical intervention, who developed a septic shock by invasive gastrointestinal aspergillosis as primary infection. Due to the unusualness of the case, despite all the measures taken, the results were obtained postmortem. We want to emphasize the need not to underestimate the possibility for an invasive aspergillosis in an immunocompetent patient. Not only pulmonary but also gastrointestinal aspergillosis should be taken into account in the differential diagnosis to avoid a delay of treatment. |
| format | Article |
| id | doaj-art-c5514ba4e6654b4297f7bb8f8342faff |
| institution | DOAJ |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-c5514ba4e6654b4297f7bb8f8342faff2025-08-20T03:22:42ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/36014233601423Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent PatientS. Guglielmetti0C. M. Jaccard1K. Mühlethaler2A. Bigler3D. Springe4L. Ebnöther5M. Delgado6Emergency Department, Bürgerspital Solothurn, SwitzerlandInstitute of Pathology, University of Bern, SwitzerlandInstitute for Infectious Diseases, University of Bern, SwitzerlandIntensive Care Unit, Anesthesiology Department, Bürgerspital Solothurn, SwitzerlandIntensive Care Unit, Anesthesiology Department, Bürgerspital Solothurn, SwitzerlandIntensive Care Unit, Anesthesiology Department, Bürgerspital Solothurn, SwitzerlandIntensive Care Unit, Anesthesiology Department, Bürgerspital Solothurn, SwitzerlandInvasive aspergillosis represents a clinical picture frequently associated with host’s immunosuppression which usually involves a high morbidity and mortality. In general, the most frequent fungal entry is the lungs with secondary hematogenous dissemination, but there are other hypotheses like a gastrointestinal portal of entry. There are some rare publications of cases with invasive aspergillosis in immunocompetent patients. We present the case of an immunocompetent patient without any risk factors except for age, ICU stay, and surgical intervention, who developed a septic shock by invasive gastrointestinal aspergillosis as primary infection. Due to the unusualness of the case, despite all the measures taken, the results were obtained postmortem. We want to emphasize the need not to underestimate the possibility for an invasive aspergillosis in an immunocompetent patient. Not only pulmonary but also gastrointestinal aspergillosis should be taken into account in the differential diagnosis to avoid a delay of treatment.http://dx.doi.org/10.1155/2020/3601423 |
| spellingShingle | S. Guglielmetti C. M. Jaccard K. Mühlethaler A. Bigler D. Springe L. Ebnöther M. Delgado Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient Case Reports in Critical Care |
| title | Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient |
| title_full | Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient |
| title_fullStr | Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient |
| title_full_unstemmed | Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient |
| title_short | Delayed Diagnosis of a Diffuse Invasive Gastrointestinal Aspergillosis in an Immunocompetent Patient |
| title_sort | delayed diagnosis of a diffuse invasive gastrointestinal aspergillosis in an immunocompetent patient |
| url | http://dx.doi.org/10.1155/2020/3601423 |
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