Revealing the role of cancer-associated fibroblast senescence in prognosis and immune landscape in pancreatic cancer
Summary: Cancer-associated fibroblasts (CAFs) represent a major contributor to tumor growth. Cellular senescence is a state of cell-cycle arrest characterized by a pro-inflammatory phenotype. The potential impact of CAF senescence on tumor progression and the tumor microenvironment (TME) remains to...
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| Main Authors: | Luyao Liu, Hai Huang, Bin Cheng, Huaping Xie, Wang Peng, Haochen Cui, Jingwen Liang, Mengdie Cao, Yilei Yang, Wei Chen, Ronghua Wang, Yuchong Zhao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224028396 |
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