Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature
Imatinib mesylate (IM), a tyrosine kinase inhibitor, has become a standard of care for the management of chronic myeloid leukemia. The safety profile of IM is favorable; however, few adverse effects such as gastrointestinal disturbances, fluid retention, skin rashes, and myelosuppression have been r...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Pigment International |
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| Online Access: | https://journals.lww.com/10.4103/pigmentinternational.pigmentinternational_52_21 |
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| author | Neerja Saraswat Shekhar Neema Sushil Kumar |
| author_facet | Neerja Saraswat Shekhar Neema Sushil Kumar |
| author_sort | Neerja Saraswat |
| collection | DOAJ |
| description | Imatinib mesylate (IM), a tyrosine kinase inhibitor, has become a standard of care for the management of chronic myeloid leukemia. The safety profile of IM is favorable; however, few adverse effects such as gastrointestinal disturbances, fluid retention, skin rashes, and myelosuppression have been reported. Hypopigmentation of the skin is a rare adverse effect of IM. In this report, we describe two cases of chronic myeloid leukemia who developed skin hypopigmentation while on IM. |
| format | Article |
| id | doaj-art-c53b0a37af184fbe97b6cf5180e7accb |
| institution | Kabale University |
| issn | 2349-5847 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pigment International |
| spelling | doaj-art-c53b0a37af184fbe97b6cf5180e7accb2025-01-06T05:04:24ZengWolters Kluwer Medknow PublicationsPigment International2349-58472024-01-01111424510.4103/pigmentinternational.pigmentinternational_52_21Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literatureNeerja SaraswatShekhar NeemaSushil KumarImatinib mesylate (IM), a tyrosine kinase inhibitor, has become a standard of care for the management of chronic myeloid leukemia. The safety profile of IM is favorable; however, few adverse effects such as gastrointestinal disturbances, fluid retention, skin rashes, and myelosuppression have been reported. Hypopigmentation of the skin is a rare adverse effect of IM. In this report, we describe two cases of chronic myeloid leukemia who developed skin hypopigmentation while on IM.https://journals.lww.com/10.4103/pigmentinternational.pigmentinternational_52_21imatinib mesylatetyrosine kinase inhibitorskin hypopigmentationvitiligo-like lesions |
| spellingShingle | Neerja Saraswat Shekhar Neema Sushil Kumar Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature Pigment International imatinib mesylate tyrosine kinase inhibitor skin hypopigmentation vitiligo-like lesions |
| title | Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature |
| title_full | Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature |
| title_fullStr | Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature |
| title_full_unstemmed | Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature |
| title_short | Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature |
| title_sort | vitiligo like lesions following imatinib mesylate therapy a case series and review of literature |
| topic | imatinib mesylate tyrosine kinase inhibitor skin hypopigmentation vitiligo-like lesions |
| url | https://journals.lww.com/10.4103/pigmentinternational.pigmentinternational_52_21 |
| work_keys_str_mv | AT neerjasaraswat vitiligolikelesionsfollowingimatinibmesylatetherapyacaseseriesandreviewofliterature AT shekharneema vitiligolikelesionsfollowingimatinibmesylatetherapyacaseseriesandreviewofliterature AT sushilkumar vitiligolikelesionsfollowingimatinibmesylatetherapyacaseseriesandreviewofliterature |