Emotional Dysfunction in Parkinson’s Disease
In addition to motor symptomatology, idiopathic Parkinson’s disease is characterized by emotional dysfunction. Depression affects some 30 to 40 percent of Parkinson patients and other psychiatric co-morbidities include anxiety and apathy. Neuropsychological and neuroimaging studies of emotional dysf...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.3233/BEN-2011-0329 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849686510468595712 |
|---|---|
| author | Lee X. Blonder John T. Slevin |
| author_facet | Lee X. Blonder John T. Slevin |
| author_sort | Lee X. Blonder |
| collection | DOAJ |
| description | In addition to motor symptomatology, idiopathic Parkinson’s disease is characterized by emotional dysfunction. Depression affects some 30 to 40 percent of Parkinson patients and other psychiatric co-morbidities include anxiety and apathy. Neuropsychological and neuroimaging studies of emotional dysfunction in Parkinson patients suggest abnormalities involving mesolimbic and mesocortical dopaminergic pathways. There is also evidence suggesting that the interaction between serotonin and dopamine systems is important in the understanding and treatment of mood disorders in Parkinson’s disease. In this review we discuss the neuropsychiatric abnormalities that accompany Parkinson's disease and describe their neuropsychological, neuropharmacologic, and neuroimaging concomitants. |
| format | Article |
| id | doaj-art-c5304ccc694b43cd8d7919d6fa09fdb1 |
| institution | DOAJ |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-c5304ccc694b43cd8d7919d6fa09fdb12025-08-20T03:22:41ZengWileyBehavioural Neurology0953-41801875-85842011-01-0124320121710.3233/BEN-2011-0329Emotional Dysfunction in Parkinson’s DiseaseLee X. Blonder0John T. Slevin1Sanders-Brown Center on Aging and Departments of Behavioral Science and Neurology, University of Kentucky College of Medicine, Lexington, KY, USADepartment of Neurology, University of Kentucky College of Medicine, and Neurology Service Veterans Affairs Medical Center, Lexington, KY, USAIn addition to motor symptomatology, idiopathic Parkinson’s disease is characterized by emotional dysfunction. Depression affects some 30 to 40 percent of Parkinson patients and other psychiatric co-morbidities include anxiety and apathy. Neuropsychological and neuroimaging studies of emotional dysfunction in Parkinson patients suggest abnormalities involving mesolimbic and mesocortical dopaminergic pathways. There is also evidence suggesting that the interaction between serotonin and dopamine systems is important in the understanding and treatment of mood disorders in Parkinson’s disease. In this review we discuss the neuropsychiatric abnormalities that accompany Parkinson's disease and describe their neuropsychological, neuropharmacologic, and neuroimaging concomitants.http://dx.doi.org/10.3233/BEN-2011-0329 |
| spellingShingle | Lee X. Blonder John T. Slevin Emotional Dysfunction in Parkinson’s Disease Behavioural Neurology |
| title | Emotional Dysfunction in Parkinson’s Disease |
| title_full | Emotional Dysfunction in Parkinson’s Disease |
| title_fullStr | Emotional Dysfunction in Parkinson’s Disease |
| title_full_unstemmed | Emotional Dysfunction in Parkinson’s Disease |
| title_short | Emotional Dysfunction in Parkinson’s Disease |
| title_sort | emotional dysfunction in parkinson s disease |
| url | http://dx.doi.org/10.3233/BEN-2011-0329 |
| work_keys_str_mv | AT leexblonder emotionaldysfunctioninparkinsonsdisease AT johntslevin emotionaldysfunctioninparkinsonsdisease |