VPS33B-dependent exosomes modulate cellular senescence of mesenchymal stem cells via an autocrine signaling pathway

VPS33B-dependent exosomes modulate cellular senescence of mesenchymal stem cells via an autocrine signaling pathway

Mesenchymal stem cell (MSC)-derived exosomes have been intensively studied for their therapeutic effects on tissue repair and regeneration. However, the specific contributions of exosomes derived from endogenous bone marrow MSCs to the maintenance of bone tissue homeostasis remain unclear. In this s...

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Bibliographic Details
Main Authors: Hehe Wang, Qi Tan, Yijuan Duan, Mingduo Wu, Bin Zuo, Jiao Li
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Experimental Gerontology
Subjects:
Senile osteoporosis
MSC senescence
Exosome
Autocrine pathway
microRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525001159
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