Retrograde Approach for Intra-arterial Chemotherapy Delivery in Retinoblastoma

Intra-arterial chemotherapy (IAC) is currently, the first-line treatment for retinoblastomas with successful cure rates. In difficult access or unsuccessful catheterization of the ophthalmic artery (OA), the middle meningeal artery is a second alternative followed by the Japanese technique using bal...

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Bibliographic Details
Main Authors: Giancarlo Saal-Zapata, Walter Durand, Alfredo Ramos, Raúl Cordero, Rodolfo Rodríguez
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-06-01
Series:Journal of Clinical Interventional Radiology ISVIR
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1727584
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Summary:Intra-arterial chemotherapy (IAC) is currently, the first-line treatment for retinoblastomas with successful cure rates. In difficult access or unsuccessful catheterization of the ophthalmic artery (OA), the middle meningeal artery is a second alternative followed by the Japanese technique using balloon. Nevertheless, when a well-developed posterior communicating artery is present, a retrograde approach to the OA through this vessel can be performed to deliver the chemotherapeutic drugs. We present a case of an unsuccessful catheterization of the OA through the internal carotid artery due to a challenging configuration of the OA/carotid siphon angle and describe an alternative form of navigation and catheterization through the posterior circulation. To our knowledge, this is the third report of a successful retrograde catheterization of the OA for IAC and constitutes an alternative route to deliver chemotherapy.
ISSN:2456-4869