Successful Pregnancy Using the NxStage Home Hemodialysis System

Pregnancy in the setting of the uremic milieu of renal disease has a lower success rate than in the normal population and is a rare event. While intensified renal replacement therapy (RRT) during pregnancy can lead to improved outcomes, most studies have focused on nocturnal hemodialysis as the main...

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Main Authors: Yasmin Brahmbhatt, Arinze Ikeme, Navjyot Bhogal, Vincenzo Berghella
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2016/1358625
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author Yasmin Brahmbhatt
Arinze Ikeme
Navjyot Bhogal
Vincenzo Berghella
author_facet Yasmin Brahmbhatt
Arinze Ikeme
Navjyot Bhogal
Vincenzo Berghella
author_sort Yasmin Brahmbhatt
collection DOAJ
description Pregnancy in the setting of the uremic milieu of renal disease has a lower success rate than in the normal population and is a rare event. While intensified renal replacement therapy (RRT) during pregnancy can lead to improved outcomes, most studies have focused on nocturnal hemodialysis as the main RRT in pregnancy. Although thousands of patients use the home NxStage System One short daily hemodialysis (SDHD) machine in the United States, pregnancy outcomes with this therapy are unknown. The NxStage System One uses low-volume dialysate and hence small and middle molecule clearance may differ compared to conventional therapies and affect pregnancy outcomes. We report a case of a successful conception and pregnancy using the home NxStage system. The NxStage system may provide an alternative to the more routinely used NHD or standard SDHD therapies for women of childbearing age.
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institution Kabale University
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series Case Reports in Nephrology
spelling doaj-art-c525707f93ab4b529f64ac0cf91128642025-02-03T06:14:07ZengWileyCase Reports in Nephrology2090-66412090-665X2016-01-01201610.1155/2016/13586251358625Successful Pregnancy Using the NxStage Home Hemodialysis SystemYasmin Brahmbhatt0Arinze Ikeme1Navjyot Bhogal2Vincenzo Berghella3Division of Nephrology, Thomas Jefferson University, 833 Chestnut Street, Suite 700, Philadelphia, PA 19107, USADivision of Nephrology, Thomas Jefferson University, 833 Chestnut Street, Suite 700, Philadelphia, PA 19107, USADivision of Nephrology, Thomas Jefferson University, 833 Chestnut Street, Suite 700, Philadelphia, PA 19107, USADepartment of Obstetrics and Gynecology, Thomas Jefferson University, 833 Chestnut Street, 1st Floor, Philadelphia, PA 19107, USAPregnancy in the setting of the uremic milieu of renal disease has a lower success rate than in the normal population and is a rare event. While intensified renal replacement therapy (RRT) during pregnancy can lead to improved outcomes, most studies have focused on nocturnal hemodialysis as the main RRT in pregnancy. Although thousands of patients use the home NxStage System One short daily hemodialysis (SDHD) machine in the United States, pregnancy outcomes with this therapy are unknown. The NxStage System One uses low-volume dialysate and hence small and middle molecule clearance may differ compared to conventional therapies and affect pregnancy outcomes. We report a case of a successful conception and pregnancy using the home NxStage system. The NxStage system may provide an alternative to the more routinely used NHD or standard SDHD therapies for women of childbearing age.http://dx.doi.org/10.1155/2016/1358625
spellingShingle Yasmin Brahmbhatt
Arinze Ikeme
Navjyot Bhogal
Vincenzo Berghella
Successful Pregnancy Using the NxStage Home Hemodialysis System
Case Reports in Nephrology
title Successful Pregnancy Using the NxStage Home Hemodialysis System
title_full Successful Pregnancy Using the NxStage Home Hemodialysis System
title_fullStr Successful Pregnancy Using the NxStage Home Hemodialysis System
title_full_unstemmed Successful Pregnancy Using the NxStage Home Hemodialysis System
title_short Successful Pregnancy Using the NxStage Home Hemodialysis System
title_sort successful pregnancy using the nxstage home hemodialysis system
url http://dx.doi.org/10.1155/2016/1358625
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AT vincenzoberghella successfulpregnancyusingthenxstagehomehemodialysissystem