Intraspecific Diversity of <i>Mycobacterium abscessus</i> Isolated from Patients with Pulmonary Lesions

The objective: to perform intraspecific differentiation of M. abscessus strains isolated from patients with pulmonary lesions using molecular genetic tests.Results. Intraspecific differentiation of 164 cultures of M. abscessus from 114 patients without cystic fibrosis showed that the subspecies M. a...

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Bibliographic Details
Main Authors: T. G. Smirnova, L. N. Chernousova, D. A. Varlamov, D. G. Sochivko, A. E. Ergeshov
Format: Article
Language:Russian
Published: New Terra Publishing House 2023-08-01
Series:Туберкулез и болезни лёгких
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Online Access:https://www.tibl-journal.com/jour/article/view/1743
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Summary:The objective: to perform intraspecific differentiation of M. abscessus strains isolated from patients with pulmonary lesions using molecular genetic tests.Results. Intraspecific differentiation of 164 cultures of M. abscessus from 114 patients without cystic fibrosis showed that the subspecies M. abscessus subsp. dominated in the analysis set (90 of 114 patients; 78,95%), followed by M. abscessus subsp. massiliense (24/114; 21,05%). In 54 examined cystic fibrosis patients excreting non-tuberculous mycobacteria, M. abscessus was most often detected (41 patients out of 54; 75,93%). Intraspecific identification of the obtained M. abscessus isolates demonstrated the prevalence of the subspecies M. abscessus subsp. abscessus (29/41; 70,73%) over M. abscessus subsp. massiliense (11/41; 26,83%). In one case, a rare M. abscessus subsp. bolletii (1/41; 2,44%) was detected.
ISSN:2075-1230
2542-1506