Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings
Familial hypercholesterolemia is a hereditary condition marked by persistent high levels of low-density lipoprotein cholesterol in the bloodstream. Alongside the severe premature cardiovascular risks it poses, this condition can manifest in early childhood with cholesterol deposits especially within...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325001839 |
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| author | Basma Dghoughi, MD Hajar Andour, MD Basma Beqqali, MD Nazik Allali, PhD Siham El Haddad, PhD Latifa Chat, PhD |
| author_facet | Basma Dghoughi, MD Hajar Andour, MD Basma Beqqali, MD Nazik Allali, PhD Siham El Haddad, PhD Latifa Chat, PhD |
| author_sort | Basma Dghoughi, MD |
| collection | DOAJ |
| description | Familial hypercholesterolemia is a hereditary condition marked by persistent high levels of low-density lipoprotein cholesterol in the bloodstream. Alongside the severe premature cardiovascular risks it poses, this condition can manifest in early childhood with cholesterol deposits especially within tendons, known as xanthomas, causing discomfort and thickening of tendons, and rarely movement limitation. Visual examination, manual palpation, and the use of ultrasound to assess tendon thickness and texture are used to suspect the diagnosis. MRI along with biological findings and familial context confirms the diagnosis pf xanthomas. Misidentifying xanthomas can lead to delays in initiating vital lipid-lowering treatments that could potentially save lives. We report the case of a 6 years old child with familial hypercholesterolemia, presented to our structure to investigate a digital flexion contracture, that revealed profound flexor tendons’ xanthomas. |
| format | Article |
| id | doaj-art-c50971cb32d84f8e8aa709b7657f65c0 |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-c50971cb32d84f8e8aa709b7657f65c02025-08-20T02:16:55ZengElsevierRadiology Case Reports1930-04332025-06-012062874287710.1016/j.radcr.2025.02.084Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findingsBasma Dghoughi, MD0Hajar Andour, MD1Basma Beqqali, MD2Nazik Allali, PhD3Siham El Haddad, PhD4Latifa Chat, PhD5Corresponding author.; Department of Mother and Child Imaging, Children Hospital of Rabat, University Hospital Center Ibn Sina of Rabat, Rabat, MoroccoDepartment of Mother and Child Imaging, Children Hospital of Rabat, University Hospital Center Ibn Sina of Rabat, Rabat, MoroccoDepartment of Mother and Child Imaging, Children Hospital of Rabat, University Hospital Center Ibn Sina of Rabat, Rabat, MoroccoDepartment of Mother and Child Imaging, Children Hospital of Rabat, University Hospital Center Ibn Sina of Rabat, Rabat, MoroccoDepartment of Mother and Child Imaging, Children Hospital of Rabat, University Hospital Center Ibn Sina of Rabat, Rabat, MoroccoDepartment of Mother and Child Imaging, Children Hospital of Rabat, University Hospital Center Ibn Sina of Rabat, Rabat, MoroccoFamilial hypercholesterolemia is a hereditary condition marked by persistent high levels of low-density lipoprotein cholesterol in the bloodstream. Alongside the severe premature cardiovascular risks it poses, this condition can manifest in early childhood with cholesterol deposits especially within tendons, known as xanthomas, causing discomfort and thickening of tendons, and rarely movement limitation. Visual examination, manual palpation, and the use of ultrasound to assess tendon thickness and texture are used to suspect the diagnosis. MRI along with biological findings and familial context confirms the diagnosis pf xanthomas. Misidentifying xanthomas can lead to delays in initiating vital lipid-lowering treatments that could potentially save lives. We report the case of a 6 years old child with familial hypercholesterolemia, presented to our structure to investigate a digital flexion contracture, that revealed profound flexor tendons’ xanthomas.http://www.sciencedirect.com/science/article/pii/S1930043325001839XanthomaFamilial hypercholesterolemiaTendon enlargementUltrasoundMRI |
| spellingShingle | Basma Dghoughi, MD Hajar Andour, MD Basma Beqqali, MD Nazik Allali, PhD Siham El Haddad, PhD Latifa Chat, PhD Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings Radiology Case Reports Xanthoma Familial hypercholesterolemia Tendon enlargement Ultrasound MRI |
| title | Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings |
| title_full | Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings |
| title_fullStr | Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings |
| title_full_unstemmed | Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings |
| title_short | Flexor tendon xanthomas revealed by digital flexion contracture: Radiological findings |
| title_sort | flexor tendon xanthomas revealed by digital flexion contracture radiological findings |
| topic | Xanthoma Familial hypercholesterolemia Tendon enlargement Ultrasound MRI |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325001839 |
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