Dilated cardiomyopathy - guidelines for personalization of care

The term dilated cardiomyopathy (DCM) refers to a family of diseases characterized by complex interactions between environment and genetic predisposition. Diagnostic tools such as cardiac magnetic resonance imaging should be systematically implemented in clinical practice to define the etiological...

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Main Authors: Antonella Spinelli, Gaetano Marino, Alfredo Macchiusi, Stefania Angela Di Fusco, Carlo Pignalberi, Furio Colivicchi
Format: Article
Language:English
Published: PAGEPress Publications 2025-04-01
Series:Monaldi Archives for Chest Disease
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Online Access:https://www.monaldi-archives.org/macd/article/view/3173
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author Antonella Spinelli
Gaetano Marino
Alfredo Macchiusi
Stefania Angela Di Fusco
Carlo Pignalberi
Furio Colivicchi
author_facet Antonella Spinelli
Gaetano Marino
Alfredo Macchiusi
Stefania Angela Di Fusco
Carlo Pignalberi
Furio Colivicchi
author_sort Antonella Spinelli
collection DOAJ
description The term dilated cardiomyopathy (DCM) refers to a family of diseases characterized by complex interactions between environment and genetic predisposition. Diagnostic tools such as cardiac magnetic resonance imaging should be systematically implemented in clinical practice to define the etiological cause and undertake a specific treatment. We present the case of a young man with DCM and severe left ventricular dysfunction. The patient has a family history of sudden cardiac death (SCD). He is affected by a psychiatric pathology and has a history of alcohol and drug addiction. Many diagnostic hypotheses have been considered for etiological research. The use of a wearable defibrillator to temporarily protect the patient from SCD risk pending the completion of the diagnostic path to establish DCM etiology and the implementation of optimal medical therapy was considered. However, because of the underlying psychiatric pathology and the possibility of poor adherence to the maintenance of the wearable device, the patients would not have been sufficiently protected. Due to the young age of the patient, it was decided to make a personalized therapeutic choice, and he underwent implantation of a subcutaneous defibrillator.
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publishDate 2025-04-01
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series Monaldi Archives for Chest Disease
spelling doaj-art-c503962622fa4e13bd8315f216b7f5152025-08-20T03:06:10ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642025-04-0110.4081/monaldi.2025.3173Dilated cardiomyopathy - guidelines for personalization of careAntonella Spinelli0https://orcid.org/0009-0007-2282-1327Gaetano Marino1https://orcid.org/0000-0002-1559-1697Alfredo Macchiusi2Stefania Angela Di Fusco3Carlo Pignalberi4https://orcid.org/0000-0001-8388-5200Furio Colivicchi5https://orcid.org/0000-0001-7187-2234Clinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital - ASL Roma 1, RomeClinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital - ASL Roma 1, RomeClinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital - ASL Roma 1, RomeClinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital - ASL Roma 1, RomeClinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital - ASL Roma 1, RomeClinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital - ASL Roma 1, Rome The term dilated cardiomyopathy (DCM) refers to a family of diseases characterized by complex interactions between environment and genetic predisposition. Diagnostic tools such as cardiac magnetic resonance imaging should be systematically implemented in clinical practice to define the etiological cause and undertake a specific treatment. We present the case of a young man with DCM and severe left ventricular dysfunction. The patient has a family history of sudden cardiac death (SCD). He is affected by a psychiatric pathology and has a history of alcohol and drug addiction. Many diagnostic hypotheses have been considered for etiological research. The use of a wearable defibrillator to temporarily protect the patient from SCD risk pending the completion of the diagnostic path to establish DCM etiology and the implementation of optimal medical therapy was considered. However, because of the underlying psychiatric pathology and the possibility of poor adherence to the maintenance of the wearable device, the patients would not have been sufficiently protected. Due to the young age of the patient, it was decided to make a personalized therapeutic choice, and he underwent implantation of a subcutaneous defibrillator. https://www.monaldi-archives.org/macd/article/view/3173Heart failuresubcutaneous defibrillator
spellingShingle Antonella Spinelli
Gaetano Marino
Alfredo Macchiusi
Stefania Angela Di Fusco
Carlo Pignalberi
Furio Colivicchi
Dilated cardiomyopathy - guidelines for personalization of care
Monaldi Archives for Chest Disease
Heart failure
subcutaneous defibrillator
title Dilated cardiomyopathy - guidelines for personalization of care
title_full Dilated cardiomyopathy - guidelines for personalization of care
title_fullStr Dilated cardiomyopathy - guidelines for personalization of care
title_full_unstemmed Dilated cardiomyopathy - guidelines for personalization of care
title_short Dilated cardiomyopathy - guidelines for personalization of care
title_sort dilated cardiomyopathy guidelines for personalization of care
topic Heart failure
subcutaneous defibrillator
url https://www.monaldi-archives.org/macd/article/view/3173
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AT stefaniaangeladifusco dilatedcardiomyopathyguidelinesforpersonalizationofcare
AT carlopignalberi dilatedcardiomyopathyguidelinesforpersonalizationofcare
AT furiocolivicchi dilatedcardiomyopathyguidelinesforpersonalizationofcare