A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals

Recent studies on utilizing biological functions of natural substances that mimic the mesoscopic structures (nanoparticles of about 50 to 500 nm) found in plant growth points and coral skeletons have been reported. After the calcium hydrogen carbonate contained in materials derived from plants and c...

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Main Authors: Akikazu Sakudo, Koichi Furusaki, Rumiko Onishi, Takashi Onodera, Yasuhiro Yoshikawa
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/3/507
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author Akikazu Sakudo
Koichi Furusaki
Rumiko Onishi
Takashi Onodera
Yasuhiro Yoshikawa
author_facet Akikazu Sakudo
Koichi Furusaki
Rumiko Onishi
Takashi Onodera
Yasuhiro Yoshikawa
author_sort Akikazu Sakudo
collection DOAJ
description Recent studies on utilizing biological functions of natural substances that mimic the mesoscopic structures (nanoparticles of about 50 to 500 nm) found in plant growth points and coral skeletons have been reported. After the calcium hydrogen carbonate contained in materials derived from plants and coral are separated, the crystals of the mesoscopic structure can be reformed by applying a high voltage under a specific set of conditions. A suspension of these mesoscopic crystals in water (CAC-717) can be used as an effective disinfectant. CAC-717 exhibits universal virucidal activity against both enveloped and non-enveloped viruses as well as bactericidal and anti-prion activity. Moreover, in comparison to sodium hypochlorite, the potency of CAC-717 as a disinfectant is less susceptible to organic substances such as albumin. The disinfection activity of CAC-717 is maintained for at least 6 years and 4 months after storage at room temperature. CAC-717 is non-irritating and harmless to humans and animals, making it a promising biosafe disinfectant. This review explores the disinfection activity of CAC-717 as well as the potential and future uses of this material.
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spelling doaj-art-c4fb653a266b46edb95a3410ba7985c82025-08-20T02:42:27ZengMDPI AGMicroorganisms2076-26072025-02-0113350710.3390/microorganisms13030507A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic CrystalsAkikazu Sakudo0Koichi Furusaki1Rumiko Onishi2Takashi Onodera3Yasuhiro Yoshikawa4School of Veterinary Medicine, Okayama University of Science, Imabari 794-8555, Ehime, JapanMineral Activation Technical Research Center, Omuta 836-0041, Fukuoka, JapanSanta Mineral Co., Ltd., Minato-ku 105-0013, Tokyo, JapanEnvironmental Science for Sustainable Development, The University of Tokyo, Bunkyo-ku 113-8657, Tokyo, JapanSchool of Veterinary Medicine, Okayama University of Science, Imabari 794-8555, Ehime, JapanRecent studies on utilizing biological functions of natural substances that mimic the mesoscopic structures (nanoparticles of about 50 to 500 nm) found in plant growth points and coral skeletons have been reported. After the calcium hydrogen carbonate contained in materials derived from plants and coral are separated, the crystals of the mesoscopic structure can be reformed by applying a high voltage under a specific set of conditions. A suspension of these mesoscopic crystals in water (CAC-717) can be used as an effective disinfectant. CAC-717 exhibits universal virucidal activity against both enveloped and non-enveloped viruses as well as bactericidal and anti-prion activity. Moreover, in comparison to sodium hypochlorite, the potency of CAC-717 as a disinfectant is less susceptible to organic substances such as albumin. The disinfection activity of CAC-717 is maintained for at least 6 years and 4 months after storage at room temperature. CAC-717 is non-irritating and harmless to humans and animals, making it a promising biosafe disinfectant. This review explores the disinfection activity of CAC-717 as well as the potential and future uses of this material.https://www.mdpi.com/2076-2607/13/3/507Ca(HCO<sub>3</sub>)<sub>2</sub>disinfectantsdisinfectioninactivationnanotechnologyprion
spellingShingle Akikazu Sakudo
Koichi Furusaki
Rumiko Onishi
Takashi Onodera
Yasuhiro Yoshikawa
A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals
Microorganisms
Ca(HCO<sub>3</sub>)<sub>2</sub>
disinfectants
disinfection
inactivation
nanotechnology
prion
title A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals
title_full A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals
title_fullStr A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals
title_full_unstemmed A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals
title_short A Review of CAC-717, a Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals
title_sort review of cac 717 a disinfectant containing calcium hydrogen carbonate mesoscopic crystals
topic Ca(HCO<sub>3</sub>)<sub>2</sub>
disinfectants
disinfection
inactivation
nanotechnology
prion
url https://www.mdpi.com/2076-2607/13/3/507
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