Effect of hydrogen sulfide on alpha-synuclein aggregation and cell viability

Effect of hydrogen sulfide on alpha-synuclein aggregation and cell viability

Abstract Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder characterized by nigrostriatal degeneration and aggregation of α-synuclein (α-Syn) with accumulation of insoluble aggregates in Lewy bodies. Familial mutations in α-Syn are associated with the development of PD. A...

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Bibliographic Details
Main Authors: Elena A. Ostrakhovitch, Eun-Suk Song, Johannah E. Stegemann, Michael McLeod, Tritia R. Yamasaki
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
α-Synuclein
Parkinson disease
Protein aggregation
Hydrogen sulfide
Online Access:https://doi.org/10.1038/s41598-025-99794-z
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