Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report
Abstract Background Clostridioides (Clostridium) difficile infection (CDI) has become an increasingly significant disease not only as healthcare-associated infection, but also as community-acquired (CA) infection worldwide. CDI caused by the NAP1/BI/027 strain is reported to be more severe, difficul...
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| Format: | Article |
| Language: | English |
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Japan Surgical Society
2021-06-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-021-01220-9 |
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| author | Masayuki Hiraki Rei Suzuki Nobuo Tanaka Hiroki Fukunaga Yoshinori Kinoshita Hayato Kimura Shusaku Tsutsui Masaru Murata Shunji Morita |
| author_facet | Masayuki Hiraki Rei Suzuki Nobuo Tanaka Hiroki Fukunaga Yoshinori Kinoshita Hayato Kimura Shusaku Tsutsui Masaru Murata Shunji Morita |
| author_sort | Masayuki Hiraki |
| collection | DOAJ |
| description | Abstract Background Clostridioides (Clostridium) difficile infection (CDI) has become an increasingly significant disease not only as healthcare-associated infection, but also as community-acquired (CA) infection worldwide. CDI caused by the NAP1/BI/027 strain is reported to be more severe, difficult to cure, and frequently associated with recurrences in North America and Europe. Case presentation A 68-year-old woman was referred to our hospital for continuous lower abdominal pain 4 weeks after eradication therapy against Helicobacter pylori. While she was treated with fasting on the suspicion of ischemic colitis, she experienced septic shock. Emergent subtotal proctocolectomy revealed fulminant pseudomembranous C. difficile colitis. The C. difficile isolate recovered from the patient was identified as ribotype 027, which has been reported to be uncommon in Japan. Conclusion We report a rare case of CA fulminant pseudomembranous colitis caused by ribotype 027 C. difficile after H. pylori eradication therapy. |
| format | Article |
| id | doaj-art-c4f01396ee2040009f5cc52a90e25481 |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-c4f01396ee2040009f5cc52a90e254812025-08-20T03:58:54ZengJapan Surgical SocietySurgical Case Reports2198-77932021-06-01711610.1186/s40792-021-01220-9Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case reportMasayuki Hiraki0Rei Suzuki1Nobuo Tanaka2Hiroki Fukunaga3Yoshinori Kinoshita4Hayato Kimura5Shusaku Tsutsui6Masaru Murata7Shunji Morita8Department of Surgery, Itami City HospitalDepartment of Surgery, Itami City HospitalDepartment of Surgery, Itami City HospitalDepartment of Surgery, Itami City HospitalDepartment of Respiratory Medicine, Itami City HospitalDepartment of Diagnostic Pathology, Itami City HospitalDepartment of Gastroenterology, Itami City HospitalDepartment of Surgery, Itami City HospitalDepartment of Surgery, Itami City HospitalAbstract Background Clostridioides (Clostridium) difficile infection (CDI) has become an increasingly significant disease not only as healthcare-associated infection, but also as community-acquired (CA) infection worldwide. CDI caused by the NAP1/BI/027 strain is reported to be more severe, difficult to cure, and frequently associated with recurrences in North America and Europe. Case presentation A 68-year-old woman was referred to our hospital for continuous lower abdominal pain 4 weeks after eradication therapy against Helicobacter pylori. While she was treated with fasting on the suspicion of ischemic colitis, she experienced septic shock. Emergent subtotal proctocolectomy revealed fulminant pseudomembranous C. difficile colitis. The C. difficile isolate recovered from the patient was identified as ribotype 027, which has been reported to be uncommon in Japan. Conclusion We report a rare case of CA fulminant pseudomembranous colitis caused by ribotype 027 C. difficile after H. pylori eradication therapy.https://doi.org/10.1186/s40792-021-01220-9Clostridioides (Clostridium) difficile infectionFulminant colitisProctocolectomyPCR-ribotype 027Helicobacter pylori eradication therapyCommunity-acquired CDI |
| spellingShingle | Masayuki Hiraki Rei Suzuki Nobuo Tanaka Hiroki Fukunaga Yoshinori Kinoshita Hayato Kimura Shusaku Tsutsui Masaru Murata Shunji Morita Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report Surgical Case Reports Clostridioides (Clostridium) difficile infection Fulminant colitis Proctocolectomy PCR-ribotype 027 Helicobacter pylori eradication therapy Community-acquired CDI |
| title | Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report |
| title_full | Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report |
| title_fullStr | Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report |
| title_full_unstemmed | Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report |
| title_short | Community-acquired fulminant Clostridioides (Clostridium) difficile infection by ribotype 027 isolate in Japan: a case report |
| title_sort | community acquired fulminant clostridioides clostridium difficile infection by ribotype 027 isolate in japan a case report |
| topic | Clostridioides (Clostridium) difficile infection Fulminant colitis Proctocolectomy PCR-ribotype 027 Helicobacter pylori eradication therapy Community-acquired CDI |
| url | https://doi.org/10.1186/s40792-021-01220-9 |
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