On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction
Aim: to investigate the role of neutrophil-to-lymphocyte ratio (NLratio) in predicting in-hospital adverse cardiac events in patients with STEMI. Methods: this was a cohort study on patients with STEMI onset ≤24 hour hospitalised in ICCU. NLratio was calculated as absolute neutrophil count divided...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2015-03-01
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| Series: | Acta Medica Indonesiana |
| Online Access: | https://mail.actamedindones.org/index.php/ijim/article/view/2 |
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| author | Anggoro B Hartopo1 Ira Puspitawati Budi Y Setianto |
| author_facet | Anggoro B Hartopo1 Ira Puspitawati Budi Y Setianto |
| author_sort | Anggoro B Hartopo1 |
| collection | DOAJ |
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Aim: to investigate the role of neutrophil-to-lymphocyte ratio (NLratio) in predicting in-hospital adverse cardiac events in patients with STEMI. Methods: this was a cohort study on patients with STEMI onset ≤24 hour hospitalised in ICCU. NLratio was calculated as absolute neutrophil count divided with lymphocyte count measured by automated blood cell counter on admission.The outcome was in-hospital adverse cardiac events,which were recorded during follow-up. The cut-off value of NLratio to predict outcome was determined by ROC curve analysis. Univariate and multivariable analysis to assess whether high NLratio was independent predictor for in-hospital adverse events were performed. Results: among165 subjects, in-hospital adverse cardiac events occurred in 49 subjects (29%). The cut-off value of NLratio was 6.2. The univariate analysis showed that NLratio >6.2 had an odd ratio of 3.19 (95% CI 1.55-6.55, p=0.002) to develop in-hospital adverse cardiac events. The multivariate analysis showed that NLratio was an independent predictor of in-hospital adverse cardiac events with an odd ratio of 4.10 (95% CI 1.59-10.54, p=0.003). Conclusion: high on-admission NLratio is an independent predictor for in-hospital adverse cardiac events in patients hospitalised for STEMI.
Key words: neutrophil-to-lymphocyte ratio, adverse cardiac events, STEMI.
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| format | Article |
| id | doaj-art-c4eb04bad1ac41779d8dc044c37c72eb |
| institution | Kabale University |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2015-03-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-c4eb04bad1ac41779d8dc044c37c72eb2025-08-20T03:36:12ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322015-03-01471On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial InfarctionAnggoro B Hartopo10Ira Puspitawati1Budi Y Setianto2Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Gadjah Mada - Dr. Sardjito Hospital, Yogyakarta, IndonesiaDepartment of Clinical Pathology, Faculty of Medicine Universitas Gadjah Mada - Dr. Sardjito Hospital, Yogyakarta, IndonesiaDepartment of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Gadjah Mada - Dr. Sardjito Hospital, Yogyakarta, Indonesia Aim: to investigate the role of neutrophil-to-lymphocyte ratio (NLratio) in predicting in-hospital adverse cardiac events in patients with STEMI. Methods: this was a cohort study on patients with STEMI onset ≤24 hour hospitalised in ICCU. NLratio was calculated as absolute neutrophil count divided with lymphocyte count measured by automated blood cell counter on admission.The outcome was in-hospital adverse cardiac events,which were recorded during follow-up. The cut-off value of NLratio to predict outcome was determined by ROC curve analysis. Univariate and multivariable analysis to assess whether high NLratio was independent predictor for in-hospital adverse events were performed. Results: among165 subjects, in-hospital adverse cardiac events occurred in 49 subjects (29%). The cut-off value of NLratio was 6.2. The univariate analysis showed that NLratio >6.2 had an odd ratio of 3.19 (95% CI 1.55-6.55, p=0.002) to develop in-hospital adverse cardiac events. The multivariate analysis showed that NLratio was an independent predictor of in-hospital adverse cardiac events with an odd ratio of 4.10 (95% CI 1.59-10.54, p=0.003). Conclusion: high on-admission NLratio is an independent predictor for in-hospital adverse cardiac events in patients hospitalised for STEMI. Key words: neutrophil-to-lymphocyte ratio, adverse cardiac events, STEMI. https://mail.actamedindones.org/index.php/ijim/article/view/2 |
| spellingShingle | Anggoro B Hartopo1 Ira Puspitawati Budi Y Setianto On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction Acta Medica Indonesiana |
| title | On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction |
| title_full | On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction |
| title_fullStr | On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction |
| title_full_unstemmed | On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction |
| title_short | On-admission High Neutrophil to Lymphocyte Ratio as Predictor of In-hospital Adverse Cardiac Event in ST-elevation Myocardial Infarction |
| title_sort | on admission high neutrophil to lymphocyte ratio as predictor of in hospital adverse cardiac event in st elevation myocardial infarction |
| url | https://mail.actamedindones.org/index.php/ijim/article/view/2 |
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