Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature

Alpha-fetoprotein-producing gastric cancer is a rare variant of gastric adenocarcinoma. This tumor is likely to be misdiagnosed, particularly in patients with liver metastasis. This rare subgroup of gastric carcinoma may show divergent differentiation on histology and may pose a diagnostic challenge...

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Main Authors: Pritinanda Mishra, Chinmayee Panigrahi, Susama Patra, Hemant K. Nayak, Manas K. Panigrahi, Subash C. Samal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_389_23
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author Pritinanda Mishra
Chinmayee Panigrahi
Susama Patra
Hemant K. Nayak
Manas K. Panigrahi
Subash C. Samal
author_facet Pritinanda Mishra
Chinmayee Panigrahi
Susama Patra
Hemant K. Nayak
Manas K. Panigrahi
Subash C. Samal
author_sort Pritinanda Mishra
collection DOAJ
description Alpha-fetoprotein-producing gastric cancer is a rare variant of gastric adenocarcinoma. This tumor is likely to be misdiagnosed, particularly in patients with liver metastasis. This rare subgroup of gastric carcinoma may show divergent differentiation on histology and may pose a diagnostic challenge to the pathologist. They have an aggressive course with a dismal prognosis.
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id doaj-art-c4e9f6e7b8474f2a9728d32b3136065e
institution DOAJ
issn 0377-4929
0974-5130
language English
publishDate 2025-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Pathology and Microbiology
spelling doaj-art-c4e9f6e7b8474f2a9728d32b3136065e2025-08-20T03:08:21ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302025-01-0168117617910.4103/ijpm.ijpm_389_23Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literaturePritinanda MishraChinmayee PanigrahiSusama PatraHemant K. NayakManas K. PanigrahiSubash C. SamalAlpha-fetoprotein-producing gastric cancer is a rare variant of gastric adenocarcinoma. This tumor is likely to be misdiagnosed, particularly in patients with liver metastasis. This rare subgroup of gastric carcinoma may show divergent differentiation on histology and may pose a diagnostic challenge to the pathologist. They have an aggressive course with a dismal prognosis.https://journals.lww.com/10.4103/ijpm.ijpm_389_23alpha-fetoprotein gastric cancerdivergent differentiationmetastasis
spellingShingle Pritinanda Mishra
Chinmayee Panigrahi
Susama Patra
Hemant K. Nayak
Manas K. Panigrahi
Subash C. Samal
Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
Indian Journal of Pathology and Microbiology
alpha-fetoprotein gastric cancer
divergent differentiation
metastasis
title Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
title_full Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
title_fullStr Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
title_full_unstemmed Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
title_short Alpha-fetoprotein producing gastric cancer with divergent differentiation: Report of a rare case with review of literature
title_sort alpha fetoprotein producing gastric cancer with divergent differentiation report of a rare case with review of literature
topic alpha-fetoprotein gastric cancer
divergent differentiation
metastasis
url https://journals.lww.com/10.4103/ijpm.ijpm_389_23
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