The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario

Background. There are no Canadian prevalence studies on pulmonary arterial hypertension (PAH) to date. We described the characteristics of treated PAH patients and the healthcare utilization and costs associated with PAH in a population of public drug plan beneficiaries in Ontario, Canada. Methods....

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Main Authors: Haris M. Vaid, Ximena Camacho, John T. Granton, Muhammad M. Mamdani, Zhan Yao, Samantha Singh, David N. Juurlink, Tara Gomes
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2016/6279250
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author Haris M. Vaid
Ximena Camacho
John T. Granton
Muhammad M. Mamdani
Zhan Yao
Samantha Singh
David N. Juurlink
Tara Gomes
author_facet Haris M. Vaid
Ximena Camacho
John T. Granton
Muhammad M. Mamdani
Zhan Yao
Samantha Singh
David N. Juurlink
Tara Gomes
author_sort Haris M. Vaid
collection DOAJ
description Background. There are no Canadian prevalence studies on pulmonary arterial hypertension (PAH) to date. We described the characteristics of treated PAH patients and the healthcare utilization and costs associated with PAH in a population of public drug plan beneficiaries in Ontario, Canada. Methods. A retrospective cross-sectional analysis was conducted between April 2010 and March 2011 to identify treated PAH patients using population-based health administrative databases. We investigated demographic and clinical characteristics of treated PAH patients and conducted a cohort study to determine treatment patterns, healthcare utilization, and associated costs, over a one-year follow-up period (March 2012). Results. We identified 326 treated PAH cases in Ontario’s publicly funded drug plan. Overall mean age was 59.4 years (±20.3 years) and over 77% of cases were women (n=251). Combination therapy was used to treat 22.9% (n=69) of cases, costing an average of $4,569 (SD $1,544) per month. Median monthly healthcare costs were $264 (IQR $96–$747) for those who survived and $2,021 (IQR $993–$6,399) for those who died over a one-year period, respectively (p<0.01). Conclusions. PAH care in Ontario is complex and has high healthcare costs. This data may help guide towards improved patient management.
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spelling doaj-art-c4e5723769f64e859e128d69841f554b2025-02-03T01:31:17ZengWileyCanadian Respiratory Journal1198-22411916-72452016-01-01201610.1155/2016/62792506279250The Characteristics of Treated Pulmonary Arterial Hypertension Patients in OntarioHaris M. Vaid0Ximena Camacho1John T. Granton2Muhammad M. Mamdani3Zhan Yao4Samantha Singh5David N. Juurlink6Tara Gomes7School of Medicine, Queen’s University, 15 Arch Street, Kingston, ON, K7L 3N6, CanadaThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, M4N 3M5, CanadaToronto General Hospital, 200 Elizabeth Street, Toronto, ON, M5G 2C4, CanadaThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, M4N 3M5, CanadaThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, M4N 3M5, CanadaThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, M4N 3M5, CanadaThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, M4N 3M5, CanadaThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, M4N 3M5, CanadaBackground. There are no Canadian prevalence studies on pulmonary arterial hypertension (PAH) to date. We described the characteristics of treated PAH patients and the healthcare utilization and costs associated with PAH in a population of public drug plan beneficiaries in Ontario, Canada. Methods. A retrospective cross-sectional analysis was conducted between April 2010 and March 2011 to identify treated PAH patients using population-based health administrative databases. We investigated demographic and clinical characteristics of treated PAH patients and conducted a cohort study to determine treatment patterns, healthcare utilization, and associated costs, over a one-year follow-up period (March 2012). Results. We identified 326 treated PAH cases in Ontario’s publicly funded drug plan. Overall mean age was 59.4 years (±20.3 years) and over 77% of cases were women (n=251). Combination therapy was used to treat 22.9% (n=69) of cases, costing an average of $4,569 (SD $1,544) per month. Median monthly healthcare costs were $264 (IQR $96–$747) for those who survived and $2,021 (IQR $993–$6,399) for those who died over a one-year period, respectively (p<0.01). Conclusions. PAH care in Ontario is complex and has high healthcare costs. This data may help guide towards improved patient management.http://dx.doi.org/10.1155/2016/6279250
spellingShingle Haris M. Vaid
Ximena Camacho
John T. Granton
Muhammad M. Mamdani
Zhan Yao
Samantha Singh
David N. Juurlink
Tara Gomes
The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
Canadian Respiratory Journal
title The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
title_full The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
title_fullStr The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
title_full_unstemmed The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
title_short The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
title_sort characteristics of treated pulmonary arterial hypertension patients in ontario
url http://dx.doi.org/10.1155/2016/6279250
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