A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness
ObjectiveTo compare the therapeutic effects of short-term spinal cord stimulation (stSCS) and long-term spinal cord stimulation (ltSCS) on patients with prolonged disorders of consciousness(pDoC).MethodsClinical data of patients with pDoC who underwent SCS surgery at Peking University International...
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Editorial Office of Medical Journal of Peking Union Medical College Hospital
2025-03-01
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| Series: | Xiehe Yixue Zazhi |
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| Online Access: | https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-1003 |
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| author | SUN Fengqiao NIU Hongchuan YANG Yi HE Jianghong ZHAO Yuanli |
| author_facet | SUN Fengqiao NIU Hongchuan YANG Yi HE Jianghong ZHAO Yuanli |
| author_sort | SUN Fengqiao |
| collection | DOAJ |
| description | ObjectiveTo compare the therapeutic effects of short-term spinal cord stimulation (stSCS) and long-term spinal cord stimulation (ltSCS) on patients with prolonged disorders of consciousness(pDoC).MethodsClinical data of patients with pDoC who underwent SCS surgery at Peking University International Hospital from January 2020 to December 2021 were retrospectively included. Patients were divided into the stSCS group and the ltSCS group based on the surgical approach. The Coma recovery scale-revised (CRS-R) was used to assess the level of consciousness before and 3 months after SCS treatment. Based on CRS-R scores, the clinical diagnosis of the patient's level of consciousenss was categorized into four levels: vegetative state, minimally conscious state minus (MCS-), MCS plus (MCS+), and emergence from the minimally conscious state(EMCS). Improvement in the clinical diagnostic level of consciousness was defined as effective treatment, and the therapeutic outcomes of the stSCS and ltSCS groups were compared.Results44.8% of patients with pDoC showed improvement in their clinical diagnostic level of consciousness after SCS treatment. Compared to preoperative scores, the CRS-R scores at 3 months postoperatively were significantly increased in both the stSCS and ltSCS groups (both P < 0.05). However, there was no significant difference in clinical efficacy between the ltSCS and stSCS groups (P=0.613).ConclusionsBoth stSCS and ltSCS can significantly improve the level of consciousness in patients with pDoC. Compared to ltSCS, stSCS may achieve comparable short-term therapeutic outcomes. |
| format | Article |
| id | doaj-art-c4e5694733c64913a0ec3efa282c7a00 |
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| issn | 1674-9081 |
| language | zho |
| publishDate | 2025-03-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj-art-c4e5694733c64913a0ec3efa282c7a002025-08-20T02:12:10ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812025-03-0116230731310.12290/xhyxzz.2024-1003A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of ConsciousnessSUN Fengqiao0NIU Hongchuan1YANG Yi2HE Jianghong3ZHAO Yuanli4Department of Neurosurgery, Peking University International Hospital, Beijing 102206, ChinaDepartment of Neurosurgery, Peking University International Hospital, Beijing 102206, ChinaDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, ChinaDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaObjectiveTo compare the therapeutic effects of short-term spinal cord stimulation (stSCS) and long-term spinal cord stimulation (ltSCS) on patients with prolonged disorders of consciousness(pDoC).MethodsClinical data of patients with pDoC who underwent SCS surgery at Peking University International Hospital from January 2020 to December 2021 were retrospectively included. Patients were divided into the stSCS group and the ltSCS group based on the surgical approach. The Coma recovery scale-revised (CRS-R) was used to assess the level of consciousness before and 3 months after SCS treatment. Based on CRS-R scores, the clinical diagnosis of the patient's level of consciousenss was categorized into four levels: vegetative state, minimally conscious state minus (MCS-), MCS plus (MCS+), and emergence from the minimally conscious state(EMCS). Improvement in the clinical diagnostic level of consciousness was defined as effective treatment, and the therapeutic outcomes of the stSCS and ltSCS groups were compared.Results44.8% of patients with pDoC showed improvement in their clinical diagnostic level of consciousness after SCS treatment. Compared to preoperative scores, the CRS-R scores at 3 months postoperatively were significantly increased in both the stSCS and ltSCS groups (both P < 0.05). However, there was no significant difference in clinical efficacy between the ltSCS and stSCS groups (P=0.613).ConclusionsBoth stSCS and ltSCS can significantly improve the level of consciousness in patients with pDoC. Compared to ltSCS, stSCS may achieve comparable short-term therapeutic outcomes.https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-1003prolonged disorder of consciousnessminimally conscious statevegetative stateshort-term spinal cord stimulationlong-term spinal cord stimulationcoma recovery scale-revised |
| spellingShingle | SUN Fengqiao NIU Hongchuan YANG Yi HE Jianghong ZHAO Yuanli A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness Xiehe Yixue Zazhi prolonged disorder of consciousness minimally conscious state vegetative state short-term spinal cord stimulation long-term spinal cord stimulation coma recovery scale-revised |
| title | A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness |
| title_full | A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness |
| title_fullStr | A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness |
| title_full_unstemmed | A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness |
| title_short | A Comparative Study on the Clinical Effects of Short-term and Long-term Spinal Cord Stimulation in Patients with Prolonged Disorders of Consciousness |
| title_sort | comparative study on the clinical effects of short term and long term spinal cord stimulation in patients with prolonged disorders of consciousness |
| topic | prolonged disorder of consciousness minimally conscious state vegetative state short-term spinal cord stimulation long-term spinal cord stimulation coma recovery scale-revised |
| url | https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-1003 |
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