FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS

The purpose of the research was studying of features of clinic, course, medical tactics and outcomes of infectious endocarditis in 25 patients suffering from “salt” drug addiction. Materials and methods: we examined 25 patients with infectious endocarditis, the host “salt” intravenously. To verify t...

Full description

Saved in:
Bibliographic Details
Main Authors: M. V. Stolbova, U. V. Liscova, N. E. Artemova, R. I. Saifutdinov, O. V. Bugrova
Format: Article
Language:Russian
Published: SINAPS LLC 2017-08-01
Series:Архивъ внутренней медицины
Subjects:
Online Access:https://www.medarhive.ru/jour/article/view/678
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849400628430766080
author M. V. Stolbova
U. V. Liscova
N. E. Artemova
R. I. Saifutdinov
O. V. Bugrova
author_facet M. V. Stolbova
U. V. Liscova
N. E. Artemova
R. I. Saifutdinov
O. V. Bugrova
author_sort M. V. Stolbova
collection DOAJ
description The purpose of the research was studying of features of clinic, course, medical tactics and outcomes of infectious endocarditis in 25 patients suffering from “salt” drug addiction. Materials and methods: we examined 25 patients with infectious endocarditis, the host “salt” intravenously. To verify the diagnosis in addition to standard studies of blood, urine, sputum, was performed transthoracic EchoCG, x-ray study of the chest (twice, at admission and before discharge of the patient from the hospital). For certain indications used diagnostic fiber-optic bronchoscopy and computed tomography of the lungs, consulted a neurologist, cardiologist, infectious disease. Results and discussion: 84% of patients diagnosed with HIV. The acute course of the disease and presence of accompanying pathology of organs and systems was observed in the majority of patients, with a predominance of neurological changes (88%). Typical meager cardiac symptoms (noise in the region of the heart were heard in 12% of patients), frequent lung as a result of pulmonary embolism (64%). Identified infectious agents (in most cases Staphylococcus aureus -32%), the defeat of the heart valves according to the EchoCG (in 72% of patients vegetation on tricuspid valve with varying degrees of regurgitation). The choice of antimicrobial medicines was optimized (cephalosporins I-III generation, aminoglycosides, vancomycin). The positive outcome of a disease was observed in 84% of patients, mortality was 16%. Conclusions: for infectious endocarditis injecting a “salt” of the drug revealed the following: acute disease; pronounced General symptoms, atypical clinical picture, involvement of the heart valves, lungs result in pulmonary embolism, early development of multiple organ failure, high mortality. In comparison with injection drug users who inject other drugs, “salt” addicts are characterized by the frequent development of infectious endocarditis, which is apparently connected with the influence of “salt” on the immune system and joining the bright and varied neurological symptoms.
format Article
id doaj-art-c4dee291090a422d9fc0dc59974d82ec
institution Kabale University
issn 2226-6704
2411-6564
language Russian
publishDate 2017-08-01
publisher SINAPS LLC
record_format Article
series Архивъ внутренней медицины
spelling doaj-art-c4dee291090a422d9fc0dc59974d82ec2025-08-20T03:37:57ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642017-08-017426727010.20514/2226-6704-2017-7-4-267-270619FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTSM. V. Stolbova0U. V. Liscova1N. E. Artemova2R. I. Saifutdinov3O. V. Bugrova4ГБОУ ВПО «Оренбургский государственный медицинский университет»ГБОУ ВПО «Оренбургский государственный медицинский университет»ГБОУ ВПО «Оренбургский государственный медицинский университет»ГБОУ ВПО «Оренбургский государственный медицинский университет»ГБОУ ВПО «Оренбургский государственный медицинский университет»The purpose of the research was studying of features of clinic, course, medical tactics and outcomes of infectious endocarditis in 25 patients suffering from “salt” drug addiction. Materials and methods: we examined 25 patients with infectious endocarditis, the host “salt” intravenously. To verify the diagnosis in addition to standard studies of blood, urine, sputum, was performed transthoracic EchoCG, x-ray study of the chest (twice, at admission and before discharge of the patient from the hospital). For certain indications used diagnostic fiber-optic bronchoscopy and computed tomography of the lungs, consulted a neurologist, cardiologist, infectious disease. Results and discussion: 84% of patients diagnosed with HIV. The acute course of the disease and presence of accompanying pathology of organs and systems was observed in the majority of patients, with a predominance of neurological changes (88%). Typical meager cardiac symptoms (noise in the region of the heart were heard in 12% of patients), frequent lung as a result of pulmonary embolism (64%). Identified infectious agents (in most cases Staphylococcus aureus -32%), the defeat of the heart valves according to the EchoCG (in 72% of patients vegetation on tricuspid valve with varying degrees of regurgitation). The choice of antimicrobial medicines was optimized (cephalosporins I-III generation, aminoglycosides, vancomycin). The positive outcome of a disease was observed in 84% of patients, mortality was 16%. Conclusions: for infectious endocarditis injecting a “salt” of the drug revealed the following: acute disease; pronounced General symptoms, atypical clinical picture, involvement of the heart valves, lungs result in pulmonary embolism, early development of multiple organ failure, high mortality. In comparison with injection drug users who inject other drugs, “salt” addicts are characterized by the frequent development of infectious endocarditis, which is apparently connected with the influence of “salt” on the immune system and joining the bright and varied neurological symptoms.https://www.medarhive.ru/jour/article/view/678infectious endocarditisnarcomaniaclinical picturediagnosticsmedicamental and physiotherapeutic rehabilitation
spellingShingle M. V. Stolbova
U. V. Liscova
N. E. Artemova
R. I. Saifutdinov
O. V. Bugrova
FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS
Архивъ внутренней медицины
infectious endocarditis
narcomania
clinical picture
diagnostics
medicamental and physiotherapeutic rehabilitation
title FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS
title_full FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS
title_fullStr FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS
title_full_unstemmed FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS
title_short FEATURES OF AN INFECTIOUS ENDOCARDITIS IN INJECTION «SALT» ADDICTS
title_sort features of an infectious endocarditis in injection salt addicts
topic infectious endocarditis
narcomania
clinical picture
diagnostics
medicamental and physiotherapeutic rehabilitation
url https://www.medarhive.ru/jour/article/view/678
work_keys_str_mv AT mvstolbova featuresofaninfectiousendocarditisininjectionsaltaddicts
AT uvliscova featuresofaninfectiousendocarditisininjectionsaltaddicts
AT neartemova featuresofaninfectiousendocarditisininjectionsaltaddicts
AT risaifutdinov featuresofaninfectiousendocarditisininjectionsaltaddicts
AT ovbugrova featuresofaninfectiousendocarditisininjectionsaltaddicts