The role of SH3RF2 in lung squamous cell carcinoma and M2 polarization: insights into LZTS2 ubiquitination

The role of SH3RF2 in lung squamous cell carcinoma and M2 polarization: insights into LZTS2 ubiquitination

Abstract Background Despite significant advancements in therapeutic approaches for lung cancer, the prognosis of lung squamous cell carcinoma (LUSC) remains suboptimal, underscoring the critical need to identify novel molecular targets and develop targeted therapeutic strategies. Through bioinformat...

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Bibliographic Details
Main Authors: Jie Yang, Zhongfei Jia, Juan Li, Chao Jiang, Xin Zhao, Yuxiang Wang, Xiaoguo Ma, Xinjian Xu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biology Direct
Subjects:
Lung squamous cell carcinoma
SH3RF2
LZTS2
Β-catenin
M2 polarization
Online Access:https://doi.org/10.1186/s13062-025-00677-0
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