Prevalence of transfusion-transmitted infections among blood donors in Koforidua, Ghana, 2016
Introduction: Transfusion-transmitted infections (TTIs) are infections of public health concern since they have the potential to be transferred from person to person through blood transfusion. This study determined the prevalence of HIV, HBV, HCV, and syphilis infections and co-infections among b...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
African Field Epidemiology Network
2024-04-01
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| Series: | Journal of Interventional Epidemiology and Public Health |
| Subjects: | |
| Online Access: | https://www.afenet-journal.net/content/article/7/18/full/ |
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| Summary: | Introduction: Transfusion-transmitted infections (TTIs) are infections of public health
concern since they have the potential to be transferred from person to person through
blood transfusion. This study determined the prevalence of HIV, HBV, HCV, and
syphilis infections and co-infections among blood donors in Koforidua, Ghana.
Methods: A cross-sectional study was carried out among blood donors who visited St.
Joseph Hospital and Koforidua Regional Hospital between January and May 2016.
Participants were interviewed on socio-demographic information and behavioral
characteristics after which 5ml of blood was drawn from each of them. The blood was
tested for HIV, HBV, HCV and syphilis infections using rapid test kits. The prevalence
of HIV, HBV, HCV and syphilis were estimated. Results: The study recruited 426
blood donors. Their median age was 23 years. Majority, 85.7% (365/426) were males,
aged 20-29 years 50.7% (216/426) and 59.1% (252/426) had secondary education. The
prevalence of HIV was 4.5%, HBV-13.2%, HCV -8.0% and syphilis -15.3% among
blood donors in Koforidua. Coinfections found were HIV - HCV 0.4%, HIV - Syphilis
0.2%, HBV - Syphilis 1.2% and HCV - Syphilis 0.4%. For the blood donors screened,
36.2% (154/426) were positive for one out of the four infections screened. The
proportion of co-infection among the blood donors for the pathogenic markers was
2.4% (10/426). Conclusion: There is a high level of pathogenic infections among
blood donors in the study area as well as co-infections. Syphilis, a bacterial infection is
the commonest and HBV-syphilis infections were the commonest co-infection.
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| ISSN: | 2664-2824 |