Structum (chondroitin sulfate) in treatment of osteoarthritis

Objective. To assess Structum (chondroitin sulfate) efficacy in treatment of osteoarthritis in Republic of Karelia. Methods. 34 pts with osteoarthritis (mean disease duration 6,44±0,67 years) were included. Functional Leken score (FLS), pain at rest and at walk on visual analog scale (VAS), pts nons...

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Main Authors: O J Varga, V K Ignatjev, N N Vesikova, I M Marusenko
Format: Article
Language:Russian
Published: IMA PRESS LLC 2003-02-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1051
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author O J Varga
V K Ignatjev
N N Vesikova
I M Marusenko
author_facet O J Varga
V K Ignatjev
N N Vesikova
I M Marusenko
author_sort O J Varga
collection DOAJ
description Objective. To assess Structum (chondroitin sulfate) efficacy in treatment of osteoarthritis in Republic of Karelia. Methods. 34 pts with osteoarthritis (mean disease duration 6,44±0,67 years) were included. Functional Leken score (FLS), pain at rest and at walk on visual analog scale (VAS), pts nonsteroidal anti-inflammatory drugs (NSAID) requirement (diclofenac daily requirement in mg), percent of pts refused NSAID treatment, achievement of clinically significant improvement (40% decrease of FLS and/or 50% decrease of NSAID requirement) were regarded as variables for the evaluation of therapy efficacy. Results. Structum administration in pts with osteoarthritis provided reduction of FLS, pain at rest and at walk, NSAID requirement and in some cases allowed to withdraw of NSAID completely. Structum has good safety and is effective in doctor and pts opinion. Conclusion. Structum is an effective drug for treatment of osteoarthritis.
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spelling doaj-art-c4c24f79b6b7408fb3165ca386daad1e2025-08-20T03:01:57ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922003-02-01411404210.14412/1995-4484-2003-1133991Structum (chondroitin sulfate) in treatment of osteoarthritisO J VargaV K IgnatjevN N VesikovaI M MarusenkoObjective. To assess Structum (chondroitin sulfate) efficacy in treatment of osteoarthritis in Republic of Karelia. Methods. 34 pts with osteoarthritis (mean disease duration 6,44±0,67 years) were included. Functional Leken score (FLS), pain at rest and at walk on visual analog scale (VAS), pts nonsteroidal anti-inflammatory drugs (NSAID) requirement (diclofenac daily requirement in mg), percent of pts refused NSAID treatment, achievement of clinically significant improvement (40% decrease of FLS and/or 50% decrease of NSAID requirement) were regarded as variables for the evaluation of therapy efficacy. Results. Structum administration in pts with osteoarthritis provided reduction of FLS, pain at rest and at walk, NSAID requirement and in some cases allowed to withdraw of NSAID completely. Structum has good safety and is effective in doctor and pts opinion. Conclusion. Structum is an effective drug for treatment of osteoarthritis.https://rsp.mediar-press.net/rsp/article/view/1051osteoarthritistreatmentchondroitin sulfatestructum
spellingShingle O J Varga
V K Ignatjev
N N Vesikova
I M Marusenko
Structum (chondroitin sulfate) in treatment of osteoarthritis
Научно-практическая ревматология
osteoarthritis
treatment
chondroitin sulfate
structum
title Structum (chondroitin sulfate) in treatment of osteoarthritis
title_full Structum (chondroitin sulfate) in treatment of osteoarthritis
title_fullStr Structum (chondroitin sulfate) in treatment of osteoarthritis
title_full_unstemmed Structum (chondroitin sulfate) in treatment of osteoarthritis
title_short Structum (chondroitin sulfate) in treatment of osteoarthritis
title_sort structum chondroitin sulfate in treatment of osteoarthritis
topic osteoarthritis
treatment
chondroitin sulfate
structum
url https://rsp.mediar-press.net/rsp/article/view/1051
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AT vkignatjev structumchondroitinsulfateintreatmentofosteoarthritis
AT nnvesikova structumchondroitinsulfateintreatmentofosteoarthritis
AT immarusenko structumchondroitinsulfateintreatmentofosteoarthritis