Chronic exercise increases plasma brain-derived neurotrophic factor levels, pancreatic islet size, and insulin tolerance in a TrkB-dependent manner.

Chronic exercise increases plasma brain-derived neurotrophic factor levels, pancreatic islet size, and insulin tolerance in a TrkB-dependent manner.

<h4>Background</h4>Physical exercise improves glucose metabolism and insulin sensitivity. Brain-derived neurotrophic factor (BDNF) enhances insulin activity in diabetic rodents. Because physical exercise modifies BDNF production, this study aimed to investigate the effects of chronic exe...

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Main Authors: Alberto Jiménez-Maldonado, Elena Roces de Álvarez-Buylla, Sergio Montero, Valery Melnikov, Elena Castro-Rodríguez, Armando Gamboa-Domínguez, Alejandrina Rodríguez-Hernández, Mónica Lemus, Jesús Muñiz Murguía
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0115177&type=printable
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