Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)

Transportation is a necessary aspect of the aquaculture industry that might induce inevitable stress and compromise product quality. In the present study, the transcriptomic profiles in the brain and liver of Chinese sea bass (Lateolabrax maculatus) were characterized after transportation stress at...

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Main Authors: Yue Su, Sarinpan Kokau, Xiao-Ning Zhang, Yun-Wei Dong
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513424005556
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author Yue Su
Sarinpan Kokau
Xiao-Ning Zhang
Yun-Wei Dong
author_facet Yue Su
Sarinpan Kokau
Xiao-Ning Zhang
Yun-Wei Dong
author_sort Yue Su
collection DOAJ
description Transportation is a necessary aspect of the aquaculture industry that might induce inevitable stress and compromise product quality. In the present study, the transcriptomic profiles in the brain and liver of Chinese sea bass (Lateolabrax maculatus) were characterized after transportation stress at two different densities (low-density: 20 kg/m3 and high-density: 40 kg/m3). Transcriptome analysis revealed that 485 and 627 differentially expressed genes (DEGs) were determined in the brain and liver from sea bass after transportation stress, respectively. KEGG enrichment analysis demonstrated that the DEGs were significantly enriched in focal adhesion, PI3K-Akt, MAPK signaling pathway, apoptosis, and circadian rhythm under transportation stress. Protein-Protein Interaction (PPI) networks showed that COL1A1, COL1A2, COL5A2, COL10A1, and COL16A1 associated with protein digestion and absorption, together with LUM, SERPINH1, and ADAMTS2 were recognized as hub genes in the brain, while JUN, NFKB1, MAPK14, MAP3K7, HSPA1, HSP90AA1, PIK3CA and PIK3R1 tightly related to MAPK and PI3K-Akt signaling pathway and SMAD3 and PPARGC1A were considered as hub genes in the liver. These results indicated that the alterations in transcripts of sea bass are primarily involved in cell adhesion, signal transduction, immune response, and metabolic regulation in response to transportation stress. Our study provides new perspectives into the molecular mechanism underlying responses to transportation and theoretical support for optimizing transportation in the Chinese sea bass.
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spelling doaj-art-c4b45ef62f334096bc540a45188f2d352025-08-20T02:51:31ZengElsevierAquaculture Reports2352-51342024-12-013910246710.1016/j.aqrep.2024.102467Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)Yue Su0Sarinpan Kokau1Xiao-Ning Zhang2Yun-Wei Dong3Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, ChinaKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China; Department of Aquaculture, Faculty of Fisheries, Kasetsart University, Bangkok 10900, ThailandKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, ChinaKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China; Correspondence to: Key Laboratory of Mariculture, Ministry of Education, Fisheries College, Ocean University of China, 5 Yushan Road, Qingdao 266003, China.Transportation is a necessary aspect of the aquaculture industry that might induce inevitable stress and compromise product quality. In the present study, the transcriptomic profiles in the brain and liver of Chinese sea bass (Lateolabrax maculatus) were characterized after transportation stress at two different densities (low-density: 20 kg/m3 and high-density: 40 kg/m3). Transcriptome analysis revealed that 485 and 627 differentially expressed genes (DEGs) were determined in the brain and liver from sea bass after transportation stress, respectively. KEGG enrichment analysis demonstrated that the DEGs were significantly enriched in focal adhesion, PI3K-Akt, MAPK signaling pathway, apoptosis, and circadian rhythm under transportation stress. Protein-Protein Interaction (PPI) networks showed that COL1A1, COL1A2, COL5A2, COL10A1, and COL16A1 associated with protein digestion and absorption, together with LUM, SERPINH1, and ADAMTS2 were recognized as hub genes in the brain, while JUN, NFKB1, MAPK14, MAP3K7, HSPA1, HSP90AA1, PIK3CA and PIK3R1 tightly related to MAPK and PI3K-Akt signaling pathway and SMAD3 and PPARGC1A were considered as hub genes in the liver. These results indicated that the alterations in transcripts of sea bass are primarily involved in cell adhesion, signal transduction, immune response, and metabolic regulation in response to transportation stress. Our study provides new perspectives into the molecular mechanism underlying responses to transportation and theoretical support for optimizing transportation in the Chinese sea bass.http://www.sciencedirect.com/science/article/pii/S2352513424005556DensityLateolabrax maculatusSea bassTranscriptomeTransportation stress
spellingShingle Yue Su
Sarinpan Kokau
Xiao-Ning Zhang
Yun-Wei Dong
Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)
Aquaculture Reports
Density
Lateolabrax maculatus
Sea bass
Transcriptome
Transportation stress
title Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)
title_full Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)
title_fullStr Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)
title_full_unstemmed Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)
title_short Transcriptomic responses to transportation stress in the juvenile Chinese sea bass (Lateolabrax maculatus)
title_sort transcriptomic responses to transportation stress in the juvenile chinese sea bass lateolabrax maculatus
topic Density
Lateolabrax maculatus
Sea bass
Transcriptome
Transportation stress
url http://www.sciencedirect.com/science/article/pii/S2352513424005556
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AT xiaoningzhang transcriptomicresponsestotransportationstressinthejuvenilechineseseabasslateolabraxmaculatus
AT yunweidong transcriptomicresponsestotransportationstressinthejuvenilechineseseabasslateolabraxmaculatus