Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages

Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages

We addressed how advanced glycation (AGE) affects the ability of apoA-IV to impair inflammation and restore the expression of genes involved in cholesterol efflux in lipopolysaccharide- (LPS-) treated macrophages. Recombinant human apoA-IV was nonenzymatically glycated by incubation with glycolaldeh...

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Main Authors: Ligia Shimabukuro Okuda, Rodrigo Tallada Iborra, Paula Ramos Pinto, Ubiratan Fabres Machado, Maria Lucia Corrêa-Giannella, Russell Pickford, Tom Woods, Margaret Anne Brimble, Kerry-Anne Rye, Marisa Passarelli
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/6515401
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