Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence

As advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of...

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Main Author: Christopher DeZorzi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/8367268
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author Christopher DeZorzi
author_facet Christopher DeZorzi
author_sort Christopher DeZorzi
collection DOAJ
description As advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of radiation therapy is radiation-induced coronary artery disease (RICAD). Although the pathophysiology of RICAD may be slightly different and more acute onset than the commonly seen “generic” coronary artery disease, it is common practice to treat RICAD in the same method as nonradiation-induced CAD. This paper summarizes the current research available on the topic and shows there is not enough research to obtain significant data about outcomes and restenosis rates of PCI or outcomes of CABG in RICAD. The aim of this review is to create a concise and easy-to-follow review of the relevant data regarding RICAD and hopefully spark further interest in future studies in this field.
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spelling doaj-art-c4a310c8bf3d4ab9abe64ea44db572682025-08-20T02:18:46ZengWileyCardiology Research and Practice2090-80162090-05972018-01-01201810.1155/2018/83672688367268Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current EvidenceChristopher DeZorzi0University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USAAs advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of radiation therapy is radiation-induced coronary artery disease (RICAD). Although the pathophysiology of RICAD may be slightly different and more acute onset than the commonly seen “generic” coronary artery disease, it is common practice to treat RICAD in the same method as nonradiation-induced CAD. This paper summarizes the current research available on the topic and shows there is not enough research to obtain significant data about outcomes and restenosis rates of PCI or outcomes of CABG in RICAD. The aim of this review is to create a concise and easy-to-follow review of the relevant data regarding RICAD and hopefully spark further interest in future studies in this field.http://dx.doi.org/10.1155/2018/8367268
spellingShingle Christopher DeZorzi
Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence
Cardiology Research and Practice
title Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence
title_full Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence
title_fullStr Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence
title_full_unstemmed Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence
title_short Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence
title_sort radiation induced coronary artery disease and its treatment a quick review of current evidence
url http://dx.doi.org/10.1155/2018/8367268
work_keys_str_mv AT christopherdezorzi radiationinducedcoronaryarterydiseaseanditstreatmentaquickreviewofcurrentevidence