Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report
Neurofibromatosis is a group of genetic disorders comprising 2 main types: type 1 neurofibromatosis (NF-1) and type 2 neurofibromatosis. The most common form is NF-1, also known as Von Recklinghausen disease. The clinical manifestations and presentation of this condition are variable. In this report...
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| Language: | English |
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Elsevier
2025-06-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325002183 |
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| author | Nadia El Mahi Amal Mojahid Hajar Siouri Hamid Ziani Siham Nasri Imane Kamaoui Imane Skiker |
| author_facet | Nadia El Mahi Amal Mojahid Hajar Siouri Hamid Ziani Siham Nasri Imane Kamaoui Imane Skiker |
| author_sort | Nadia El Mahi |
| collection | DOAJ |
| description | Neurofibromatosis is a group of genetic disorders comprising 2 main types: type 1 neurofibromatosis (NF-1) and type 2 neurofibromatosis. The most common form is NF-1, also known as Von Recklinghausen disease. The clinical manifestations and presentation of this condition are variable. In this report, we present a unique case of a 10-year-old child with NF-1 who presented with scrotal swelling associated with progressive penile enlargement. After a thorough evaluation, the diagnosis of a plexiform neurofibroma was made. MRI evaluation revealed an intrapelvic extension of the tumor affecting the bladder and spermatic cords. This rare clinical presentation makes this case particularly interesting and highlights the diverse manifestations of Von Recklinghausen disease. |
| format | Article |
| id | doaj-art-c497545ac3f94a659ef0804ddcfd197b |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-c497545ac3f94a659ef0804ddcfd197b2025-08-20T02:16:55ZengElsevierRadiology Case Reports1930-04332025-06-012063116311910.1016/j.radcr.2025.03.008Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case reportNadia El Mahi0Amal Mojahid1Hajar Siouri2Hamid Ziani3Siham Nasri4Imane Kamaoui5Imane Skiker6Corresponding author.; Department of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoDepartment of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoDepartment of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoDepartment of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoDepartment of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoDepartment of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoDepartment of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, MoroccoNeurofibromatosis is a group of genetic disorders comprising 2 main types: type 1 neurofibromatosis (NF-1) and type 2 neurofibromatosis. The most common form is NF-1, also known as Von Recklinghausen disease. The clinical manifestations and presentation of this condition are variable. In this report, we present a unique case of a 10-year-old child with NF-1 who presented with scrotal swelling associated with progressive penile enlargement. After a thorough evaluation, the diagnosis of a plexiform neurofibroma was made. MRI evaluation revealed an intrapelvic extension of the tumor affecting the bladder and spermatic cords. This rare clinical presentation makes this case particularly interesting and highlights the diverse manifestations of Von Recklinghausen disease.http://www.sciencedirect.com/science/article/pii/S1930043325002183ChildVon RecklinghausenScrotumPenisBladderSpermatic cord |
| spellingShingle | Nadia El Mahi Amal Mojahid Hajar Siouri Hamid Ziani Siham Nasri Imane Kamaoui Imane Skiker Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report Radiology Case Reports Child Von Recklinghausen Scrotum Penis Bladder Spermatic cord |
| title | Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report |
| title_full | Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report |
| title_fullStr | Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report |
| title_full_unstemmed | Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report |
| title_short | Rare uro-genital manifestations of von Recklinghausen disease: Scrotal, penile, and intrapelvic involvement with bladder and spermatic cord extension: A case report |
| title_sort | rare uro genital manifestations of von recklinghausen disease scrotal penile and intrapelvic involvement with bladder and spermatic cord extension a case report |
| topic | Child Von Recklinghausen Scrotum Penis Bladder Spermatic cord |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325002183 |
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