Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.

Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.

<h4>Background</h4>Limited knowledge exists on early HIV events that may inform preventive and therapeutic strategies. This study aims to characterize the earliest immunologic and virologic HIV events following infection and investigates the usage of a novel therapeutic strategy.<h4&g...

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Main Authors: Jintanat Ananworanich, Alexandra Schuetz, Claire Vandergeeten, Irini Sereti, Mark de Souza, Rungsun Rerknimitr, Robin Dewar, Mary Marovich, Frits van Griensven, Rafick Sekaly, Suteeraporn Pinyakorn, Nittaya Phanuphak, Rapee Trichavaroj, Wiriya Rutvisuttinunt, Nitiya Chomchey, Robert Paris, Sheila Peel, Victor Valcour, Frank Maldarelli, Nicolas Chomont, Nelson Michael, Praphan Phanuphak, Jerome H Kim, RV254/SEARCH 010 Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0033948&type=printable
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