Manganese Superoxide Dismutase: Structure, Function, and Implications in Human Disease
Manganese superoxide dismutase (MnSOD) is a vital mitochondrial antioxidant enzyme that preserves cellular integrity by catalyzing the dismutation of superoxide radicals into hydrogen peroxide. Its central role in maintaining redox homeostasis has positioned it as a key target in biomedical research...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-07-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/14/7/848 |
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| Summary: | Manganese superoxide dismutase (MnSOD) is a vital mitochondrial antioxidant enzyme that preserves cellular integrity by catalyzing the dismutation of superoxide radicals into hydrogen peroxide. Its central role in maintaining redox homeostasis has positioned it as a key target in biomedical research. This review provides an in-depth examination of MnSOD’s structural and functional properties, regulatory mechanisms, and its involvement in the pathogenesis of various human diseases. |
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| ISSN: | 2076-3921 |