Myasthenia gravis with Castleman disease: A case report with review of literature
Myasthenia gravis is an autoimmune disorder caused by the formation of autoantibodies directed against the synapses of neuromuscular junction. It is most commonly associated with other non-thymomatous lesions. Castleman disease is one of them, which is a benign lymphoproliferative disorder of uncert...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_482_23 |
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| author | Sujit Nandy Debashis Bhattacharya Somenath Kundu Uttara Chatterjee |
| author_facet | Sujit Nandy Debashis Bhattacharya Somenath Kundu Uttara Chatterjee |
| author_sort | Sujit Nandy |
| collection | DOAJ |
| description | Myasthenia gravis is an autoimmune disorder caused by the formation of autoantibodies directed against the synapses of neuromuscular junction. It is most commonly associated with other non-thymomatous lesions. Castleman disease is one of them, which is a benign lymphoproliferative disorder of uncertain origin. Only eight cases of myasthenia gravis associated with Castleman disease have been described so far. Here, we take the opportunity to describe a case of myasthenia gravis with Castleman disease simulating thymoma clinically and radiologically along with review of literature of this rare association. Patient developed myasthenic crisis in the immediate post-operative period which is more common in myasthenia gravis with Castleman disease rather than myasthenia gravis with thymoma. |
| format | Article |
| id | doaj-art-c48094d086044a2ea83e44fca6eb17a9 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-c48094d086044a2ea83e44fca6eb17a92025-08-20T03:36:18ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302025-04-0168239239410.4103/ijpm.ijpm_482_23Myasthenia gravis with Castleman disease: A case report with review of literatureSujit NandyDebashis BhattacharyaSomenath KunduUttara ChatterjeeMyasthenia gravis is an autoimmune disorder caused by the formation of autoantibodies directed against the synapses of neuromuscular junction. It is most commonly associated with other non-thymomatous lesions. Castleman disease is one of them, which is a benign lymphoproliferative disorder of uncertain origin. Only eight cases of myasthenia gravis associated with Castleman disease have been described so far. Here, we take the opportunity to describe a case of myasthenia gravis with Castleman disease simulating thymoma clinically and radiologically along with review of literature of this rare association. Patient developed myasthenic crisis in the immediate post-operative period which is more common in myasthenia gravis with Castleman disease rather than myasthenia gravis with thymoma.https://journals.lww.com/10.4103/ijpm.ijpm_482_23castleman diseasemyasthenia gravisnon-thymomatous lesions associated with myasthenia gravis |
| spellingShingle | Sujit Nandy Debashis Bhattacharya Somenath Kundu Uttara Chatterjee Myasthenia gravis with Castleman disease: A case report with review of literature Indian Journal of Pathology and Microbiology castleman disease myasthenia gravis non-thymomatous lesions associated with myasthenia gravis |
| title | Myasthenia gravis with Castleman disease: A case report with review of literature |
| title_full | Myasthenia gravis with Castleman disease: A case report with review of literature |
| title_fullStr | Myasthenia gravis with Castleman disease: A case report with review of literature |
| title_full_unstemmed | Myasthenia gravis with Castleman disease: A case report with review of literature |
| title_short | Myasthenia gravis with Castleman disease: A case report with review of literature |
| title_sort | myasthenia gravis with castleman disease a case report with review of literature |
| topic | castleman disease myasthenia gravis non-thymomatous lesions associated with myasthenia gravis |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_482_23 |
| work_keys_str_mv | AT sujitnandy myastheniagraviswithcastlemandiseaseacasereportwithreviewofliterature AT debashisbhattacharya myastheniagraviswithcastlemandiseaseacasereportwithreviewofliterature AT somenathkundu myastheniagraviswithcastlemandiseaseacasereportwithreviewofliterature AT uttarachatterjee myastheniagraviswithcastlemandiseaseacasereportwithreviewofliterature |