Comprehensive analysis of pyroptosis-related genes in psoriasis and targeted gene editing of CASP1 and CASP5 using lipid nanoparticles to alleviate skin inflammation
Psoriasis is a chronic inflammatory skin disorder driven by immune dysregulation and excessive cell death. Pyroptosis, a form of inflammatory programmed cell death, has not been extensively studied in the context of psoriasis despite its importance in inflammation. In this study, we systematically a...
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| Main Authors: | Gexiao Xu, Guanyi Ma, Jiachen Sun, Xiaoyan Yu, Jie Sun, Bing Gao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1639869/full |
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