Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy

Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy

Abstract Piezocatalyst‐enabled sonopiezoelectric therapy offers noninvasive treatment with high spatiotemporal selectivity, yet existing piezocatalysts are limited by suboptimal efficacy, cancer cell resistance to oxidative stress, and biosafety concerns. Here, hafnia (HfO2), one of the only few FDA...

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Bibliographic Details
Main Authors: Linhong Zhong, Xun Guo, Liming Deng, Xiaoting Wang, Hongye He, Nianhong Wu, Rui Tang, Liang Chen, Yu Chen, Pan Li
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
enzymatic activity
hafnium oxide
nanocatalytic therapy
PANoptosis
piezoelectric biomaterials
Online Access:https://doi.org/10.1002/advs.202500406
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