The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar
BackgroundStudies conducted on Western populations have shown that the Clinical Frailty Scale (CFS) is a major predictor of adverse outcomes in older patients with hip fractures; however, there are no data on Middle Eastern populations, who may be culturally and ethnically different. We examined the...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1643181/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849731191328997376 |
|---|---|
| author | Shirmila Syamala Francisco José Tarazona-Santabalbina Francisco José Tarazona-Santabalbina Jorge Luis Passarelli Brijesh Sathian Navas Nadukkandiyil Hanadi Al Hamad |
| author_facet | Shirmila Syamala Francisco José Tarazona-Santabalbina Francisco José Tarazona-Santabalbina Jorge Luis Passarelli Brijesh Sathian Navas Nadukkandiyil Hanadi Al Hamad |
| author_sort | Shirmila Syamala |
| collection | DOAJ |
| description | BackgroundStudies conducted on Western populations have shown that the Clinical Frailty Scale (CFS) is a major predictor of adverse outcomes in older patients with hip fractures; however, there are no data on Middle Eastern populations, who may be culturally and ethnically different. We examined the association between the preoperative Clinical Frailty Scale and multiple adverse outcomes in a cohort of patients with hip fractures (aged 60–96 years) in Qatar.MethodsThis prospective, single-center observational cohort study included 155 patients aged ≥ 60 years with hip fractures from Qatar. These patients underwent a Clinical Frailty Scale assessment at baseline and were followed to evaluate four outcomes of interest: incident delirium, postoperative complications, all-cause mortality within a year, and increased length of stay (LoS) (LoS ≥ 14 days).ResultsA total of 155 patients with hip fractures (average age 74.6 years, 46.5% women) were included in the study. At baseline, 72.2% had a Clinical Frailty Scale score of <5, 12.3% had a score of 5, and 15.5% had a score > 5. Higher baseline scores on the Clinical Frailty Scale were strongly and positively associated with delirium, postoperative complications, and all-cause mortality, but there was no association with length of hospital stay. Compared to the patients with Clinical Frailty Scale scores < 5, those with scores > 5 had significantly higher multivariable risk ratios (RR) (with 95% confidence interval [CI]) for various outcomes. Specifically, the RR for delirium was 7.76 (3.17–18.97), for postoperative complications, it was 3.59 (1.20–10.77), for all-cause mortality, it was 6.39 (1.45–28.20), and for length of stay ≥14 days, it was 1.43 (0.75–2.73).ConclusionThe Clinical Frailty Scale was positively associated with delirium, postoperative complications, and all-cause mortality but not with length of hospital stay in patients with hip fractures from Qatar. |
| format | Article |
| id | doaj-art-c477e4dc5fff4d1aad32a3930dedccde |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-c477e4dc5fff4d1aad32a3930dedccde2025-08-20T03:08:37ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-07-011210.3389/fmed.2025.16431811643181The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in QatarShirmila Syamala0Francisco José Tarazona-Santabalbina1Francisco José Tarazona-Santabalbina2Jorge Luis Passarelli3Brijesh Sathian4Navas Nadukkandiyil5Hanadi Al Hamad6Department of Geriatrics and Long-Term Care, Hamad Medical Corporation, Doha, QatarGeriatric Medicine Department, Hospital Universitario de la Ribera, Alzira, SpainMedical School, Universitat Catòlica de València Sant Vicent Màrtir, Valencia, SpainDepartment of Geriatrics and Long-Term Care, Hamad Medical Corporation, Doha, QatarDepartment of Geriatrics and Long-Term Care, Hamad Medical Corporation, Doha, QatarDepartment of Geriatrics and Long-Term Care, Hamad Medical Corporation, Doha, QatarDepartment of Geriatrics and Long-Term Care, Hamad Medical Corporation, Doha, QatarBackgroundStudies conducted on Western populations have shown that the Clinical Frailty Scale (CFS) is a major predictor of adverse outcomes in older patients with hip fractures; however, there are no data on Middle Eastern populations, who may be culturally and ethnically different. We examined the association between the preoperative Clinical Frailty Scale and multiple adverse outcomes in a cohort of patients with hip fractures (aged 60–96 years) in Qatar.MethodsThis prospective, single-center observational cohort study included 155 patients aged ≥ 60 years with hip fractures from Qatar. These patients underwent a Clinical Frailty Scale assessment at baseline and were followed to evaluate four outcomes of interest: incident delirium, postoperative complications, all-cause mortality within a year, and increased length of stay (LoS) (LoS ≥ 14 days).ResultsA total of 155 patients with hip fractures (average age 74.6 years, 46.5% women) were included in the study. At baseline, 72.2% had a Clinical Frailty Scale score of <5, 12.3% had a score of 5, and 15.5% had a score > 5. Higher baseline scores on the Clinical Frailty Scale were strongly and positively associated with delirium, postoperative complications, and all-cause mortality, but there was no association with length of hospital stay. Compared to the patients with Clinical Frailty Scale scores < 5, those with scores > 5 had significantly higher multivariable risk ratios (RR) (with 95% confidence interval [CI]) for various outcomes. Specifically, the RR for delirium was 7.76 (3.17–18.97), for postoperative complications, it was 3.59 (1.20–10.77), for all-cause mortality, it was 6.39 (1.45–28.20), and for length of stay ≥14 days, it was 1.43 (0.75–2.73).ConclusionThe Clinical Frailty Scale was positively associated with delirium, postoperative complications, and all-cause mortality but not with length of hospital stay in patients with hip fractures from Qatar.https://www.frontiersin.org/articles/10.3389/fmed.2025.1643181/fullfrailtyClinical Frailty ScaledeliriummortalityQatarMiddle East |
| spellingShingle | Shirmila Syamala Francisco José Tarazona-Santabalbina Francisco José Tarazona-Santabalbina Jorge Luis Passarelli Brijesh Sathian Navas Nadukkandiyil Hanadi Al Hamad The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar Frontiers in Medicine frailty Clinical Frailty Scale delirium mortality Qatar Middle East |
| title | The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar |
| title_full | The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar |
| title_fullStr | The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar |
| title_full_unstemmed | The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar |
| title_short | The Clinical Frailty Scale and incidence of adverse outcomes in older patients with hip fractures in Qatar |
| title_sort | clinical frailty scale and incidence of adverse outcomes in older patients with hip fractures in qatar |
| topic | frailty Clinical Frailty Scale delirium mortality Qatar Middle East |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1643181/full |
| work_keys_str_mv | AT shirmilasyamala theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT franciscojosetarazonasantabalbina theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT franciscojosetarazonasantabalbina theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT jorgeluispassarelli theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT brijeshsathian theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT navasnadukkandiyil theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT hanadialhamad theclinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT shirmilasyamala clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT franciscojosetarazonasantabalbina clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT franciscojosetarazonasantabalbina clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT jorgeluispassarelli clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT brijeshsathian clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT navasnadukkandiyil clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar AT hanadialhamad clinicalfrailtyscaleandincidenceofadverseoutcomesinolderpatientswithhipfracturesinqatar |