Lebanese Cannabis sativa L. extract protects from cisplatin-induced nephrotoxicity in mice by inhibiting podocytes apoptosis

Lebanese Cannabis sativa L. extract protects from cisplatin-induced nephrotoxicity in mice by inhibiting podocytes apoptosis

Abstract Background Cisplatin is an anti-cancer drug used to treat a plethora of solid tumors. However, it is associated with dose dependent nephrotoxicity limiting its use as anticancer agent. Objective The current study aimed to investigate the nephroprotective effect of native Lebanese Cannabis s...

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Bibliographic Details
Main Authors: Alia Khalil, Sahar Al Toufaily, Wassim Shebaby, Marissa El Hage, Dima Mroue, Wissam Faour, Mohamad Mroueh
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Cannabis Research
Subjects:
Cannabis sativa
Cisplatin
Nephrotoxicity
Podocytes
Cisplatin-induced nephrotoxicity
Online Access:https://doi.org/10.1186/s42238-025-00260-4
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