Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan
Abstract Objective This study aimed to evaluate the use of video capsule endoscopy (VCE) in patients with obscure gastrointestinal bleeding (OGIB), compare cases of overt and occult OGIB, assess the rates of balloon‐assisted enteroscopy (BAE) interventions and rebleeding, and identify predictive mar...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-04-01
|
| Series: | DEN Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/deo2.354 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849397691232026624 |
|---|---|
| author | Anna Tojo Tomohisa Sujino Yukie Hayashi Kenji J L Limpias Kamiya Moe Sato Sakurai Hinako Yusuke Yoshimatsu Satoshi Kinoshita Hiroki Kiyohara Yohei Mikami Kaoru Takabayashi Motohiko Kato Haruhiko Ogata Takanori Kanai Naoki Hosoe |
| author_facet | Anna Tojo Tomohisa Sujino Yukie Hayashi Kenji J L Limpias Kamiya Moe Sato Sakurai Hinako Yusuke Yoshimatsu Satoshi Kinoshita Hiroki Kiyohara Yohei Mikami Kaoru Takabayashi Motohiko Kato Haruhiko Ogata Takanori Kanai Naoki Hosoe |
| author_sort | Anna Tojo |
| collection | DOAJ |
| description | Abstract Objective This study aimed to evaluate the use of video capsule endoscopy (VCE) in patients with obscure gastrointestinal bleeding (OGIB), compare cases of overt and occult OGIB, assess the rates of balloon‐assisted enteroscopy (BAE) interventions and rebleeding, and identify predictive markers of positive VCE findings. Methods Medical records of 430 patients who underwent VCE for OGIB between 2004 and 2022 were analyzed. Occult OGIB was defined as IDA or positive fecal occult blood, whereas overt OGIB was defined as clinically imperceptible bleeding. We retrospectively analyzed demographics, VCE findings based on Saurin classification (P0, P1, and P2), outcome of BAE interventions, and rebleeding rates. Results A total of 253 patients with overt OGIB and 177 with occult OGIB were included. P1 findings were predominant in both groups, with a similar distribution. The percentage of patients receiving conservative therapy was higher in P1 than in P2 for both overt and occult OGIB. BAE was more frequently performed in P2 than in P1 VCE (83.0% vs. 35.3% in overt OGIB, 84.4% vs. 24.4% in occult OGIB). The percentage of positive findings and intervention in total BAE performed patients were comparable in P1 and P2 of overt OGIB, whereas these percentages in P2 were more than P1 of occult OGIB. Conclusion VCE effectively identified OGIB lesions requiring intervention, particularly occult OGIB lesions, potentially reducing unnecessary BAE. Rebleeding rates varied according to the VCE findings, emphasizing the importance of follow‐up in high‐risk patients. |
| format | Article |
| id | doaj-art-c47014fe8bb54f13a6ec9ce2260de1b2 |
| institution | Kabale University |
| issn | 2692-4609 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-c47014fe8bb54f13a6ec9ce2260de1b22025-08-20T03:38:54ZengWileyDEN Open2692-46092024-04-0141n/an/a10.1002/deo2.354Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in JapanAnna Tojo0Tomohisa Sujino1Yukie Hayashi2Kenji J L Limpias Kamiya3Moe Sato4Sakurai Hinako5Yusuke Yoshimatsu6Satoshi Kinoshita7Hiroki Kiyohara8Yohei Mikami9Kaoru Takabayashi10Motohiko Kato11Haruhiko Ogata12Takanori Kanai13Naoki Hosoe14Division of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanCenter for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanDepartment of Gastroenterology Saitama Medical Center Saitama JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanCenter for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo JapanCenter for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo JapanCenter for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo JapanCenter for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo JapanAbstract Objective This study aimed to evaluate the use of video capsule endoscopy (VCE) in patients with obscure gastrointestinal bleeding (OGIB), compare cases of overt and occult OGIB, assess the rates of balloon‐assisted enteroscopy (BAE) interventions and rebleeding, and identify predictive markers of positive VCE findings. Methods Medical records of 430 patients who underwent VCE for OGIB between 2004 and 2022 were analyzed. Occult OGIB was defined as IDA or positive fecal occult blood, whereas overt OGIB was defined as clinically imperceptible bleeding. We retrospectively analyzed demographics, VCE findings based on Saurin classification (P0, P1, and P2), outcome of BAE interventions, and rebleeding rates. Results A total of 253 patients with overt OGIB and 177 with occult OGIB were included. P1 findings were predominant in both groups, with a similar distribution. The percentage of patients receiving conservative therapy was higher in P1 than in P2 for both overt and occult OGIB. BAE was more frequently performed in P2 than in P1 VCE (83.0% vs. 35.3% in overt OGIB, 84.4% vs. 24.4% in occult OGIB). The percentage of positive findings and intervention in total BAE performed patients were comparable in P1 and P2 of overt OGIB, whereas these percentages in P2 were more than P1 of occult OGIB. Conclusion VCE effectively identified OGIB lesions requiring intervention, particularly occult OGIB lesions, potentially reducing unnecessary BAE. Rebleeding rates varied according to the VCE findings, emphasizing the importance of follow‐up in high‐risk patients.https://doi.org/10.1002/deo2.354double‐balloon enteroscopyobscure gastrointestinal bleeding (OGIB)overt and occult OGIBsingle‐balloon enteroscopyvideo capsule endoscopy |
| spellingShingle | Anna Tojo Tomohisa Sujino Yukie Hayashi Kenji J L Limpias Kamiya Moe Sato Sakurai Hinako Yusuke Yoshimatsu Satoshi Kinoshita Hiroki Kiyohara Yohei Mikami Kaoru Takabayashi Motohiko Kato Haruhiko Ogata Takanori Kanai Naoki Hosoe Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan DEN Open double‐balloon enteroscopy obscure gastrointestinal bleeding (OGIB) overt and occult OGIB single‐balloon enteroscopy video capsule endoscopy |
| title | Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan |
| title_full | Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan |
| title_fullStr | Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan |
| title_full_unstemmed | Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan |
| title_short | Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan |
| title_sort | video capsule endoscopy in overt and occult obscure gastrointestinal bleeding insights from a single center observational study in japan |
| topic | double‐balloon enteroscopy obscure gastrointestinal bleeding (OGIB) overt and occult OGIB single‐balloon enteroscopy video capsule endoscopy |
| url | https://doi.org/10.1002/deo2.354 |
| work_keys_str_mv | AT annatojo videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT tomohisasujino videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT yukiehayashi videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT kenjijllimpiaskamiya videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT moesato videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT sakuraihinako videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT yusukeyoshimatsu videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT satoshikinoshita videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT hirokikiyohara videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT yoheimikami videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT kaorutakabayashi videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT motohikokato videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT haruhikoogata videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT takanorikanai videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan AT naokihosoe videocapsuleendoscopyinovertandoccultobscuregastrointestinalbleedinginsightsfromasinglecenterobservationalstudyinjapan |