The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018)
Aim of review. To analyze the options of application of Lactobacillus reuteri DSMZ17648 (Pylopass™) within Helicobacter pylori eradication. Summary. H. pylori eradication therapy is considered as one of the optional spheres for clinical application of probiotic medications. According to available da...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Gastro LLC
2018-08-01
|
| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| Subjects: | |
| Online Access: | https://www.gastro-j.ru/jour/article/view/238 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823860308032094208 |
|---|---|
| author | V. T. Ivashkin O. P. Alekseyeva A. Yu. Baranovsky Ye. K. Baranskaya Ye. V. Beloborodova T. A. Kolesov N. V. Korochanskaya K. . Lang T. L. Lapina I. V. Mayev M. V. Mokshina D. L. Nepomnyashchy Ye. V. Onuchina R. G. Sayfutdinov T. H. Sviridova V. I. Simanenkov A. V. Tkachev A. S. Trukhmanov L. P. Faizova I. B. Khlynov O. B. Khlynova A. A. Sheptulin |
| author_facet | V. T. Ivashkin O. P. Alekseyeva A. Yu. Baranovsky Ye. K. Baranskaya Ye. V. Beloborodova T. A. Kolesov N. V. Korochanskaya K. . Lang T. L. Lapina I. V. Mayev M. V. Mokshina D. L. Nepomnyashchy Ye. V. Onuchina R. G. Sayfutdinov T. H. Sviridova V. I. Simanenkov A. V. Tkachev A. S. Trukhmanov L. P. Faizova I. B. Khlynov O. B. Khlynova A. A. Sheptulin |
| author_sort | V. T. Ivashkin |
| collection | DOAJ |
| description | Aim of review. To analyze the options of application of Lactobacillus reuteri DSMZ17648 (Pylopass™) within Helicobacter pylori eradication. Summary. H. pylori eradication therapy is considered as one of the optional spheres for clinical application of probiotic medications. According to available data certain strains of probiotics are effective in decreasing of gastrointestinal adverse effects rates, associated with eradication therapy while the other can potentiate the efficacy of H. pylori eradication itself. L. reuteri strain DSM17648 which was chosen from over 700 wildtype strains of Lactobacillus spp. possess the ability for selective adhesion to H. pylori in vivo in the gastric media. DSM17648 strain of L. reuteri form coaggregates with various H. pylori strains and serotypes both in vivo and in vitro. It was revealed that lyophilizate of this strain (PylopassTM) blocks adhesion of H. pylori to epithelial cells as well. Clinical trials demonstrate the effect of PylopassTMon gastric mucosa colonization by H. pylori according to the 13C urea breath test data and as well the increase in H. pylori eradication rate when the productis added the to triple therapy modes. Conclusion. Potential of PylopassTM combination to various H. pylori eradication therapy modes is a subject offutnet multicenter randomized clinical trials for assessment of optimal combination to antibiotic drugs, treatment duration and adverse effect rates. The value of monotherapy by this metabiotic at chronic H. pyloriassociated gastritis is a subject of further studies. |
| format | Article |
| id | doaj-art-c46ee1115cb6432c90d0cf6ef0126d4d |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2018-08-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-c46ee1115cb6432c90d0cf6ef0126d4d2025-02-10T16:14:29ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732018-08-01283333810.22416/1382-4376-2018-28-3-33-38238The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018)V. T. Ivashkin0O. P. Alekseyeva1A. Yu. Baranovsky2Ye. K. Baranskaya3Ye. V. Beloborodova4T. A. Kolesov5N. V. Korochanskaya6K. . Lang7T. L. Lapina8I. V. Mayev9M. V. Mokshina10D. L. Nepomnyashchy11Ye. V. Onuchina12R. G. Sayfutdinov13T. H. Sviridova14V. I. Simanenkov15A. V. Tkachev16A. S. Trukhmanov17L. P. Faizova18I. B. Khlynov19O. B. Khlynova20A. A. Sheptulin21Sechenov First Moscow State Medical UniversitySemashko Nizhny Novgorod regional clinical hospitalSt. Petersburg UniversitySechenov First Moscow State Medical UniversitySiberian State Medical UniversitySeredavin Samara regional clinical hospitalKuban state medical UniversityOrganobalance GmbHSechenov First Moscow State Medical UniversityYevdokimov Moscow State University of Medicine and DentistryPacific state medical universityNovosibirsk state medical universityIrkutsk state medical academy of postgraduate educationKazan state medical academyBurdenko Voronezh state medical universityMechnikov Northwest state medical universityRostov state medical universitySechenov First Moscow State Medical University6 Bashkir state medical universityUral state medical universityVagner Perm state medical universitySechenov First Moscow State Medical UniversityAim of review. To analyze the options of application of Lactobacillus reuteri DSMZ17648 (Pylopass™) within Helicobacter pylori eradication. Summary. H. pylori eradication therapy is considered as one of the optional spheres for clinical application of probiotic medications. According to available data certain strains of probiotics are effective in decreasing of gastrointestinal adverse effects rates, associated with eradication therapy while the other can potentiate the efficacy of H. pylori eradication itself. L. reuteri strain DSM17648 which was chosen from over 700 wildtype strains of Lactobacillus spp. possess the ability for selective adhesion to H. pylori in vivo in the gastric media. DSM17648 strain of L. reuteri form coaggregates with various H. pylori strains and serotypes both in vivo and in vitro. It was revealed that lyophilizate of this strain (PylopassTM) blocks adhesion of H. pylori to epithelial cells as well. Clinical trials demonstrate the effect of PylopassTMon gastric mucosa colonization by H. pylori according to the 13C urea breath test data and as well the increase in H. pylori eradication rate when the productis added the to triple therapy modes. Conclusion. Potential of PylopassTM combination to various H. pylori eradication therapy modes is a subject offutnet multicenter randomized clinical trials for assessment of optimal combination to antibiotic drugs, treatment duration and adverse effect rates. The value of monotherapy by this metabiotic at chronic H. pyloriassociated gastritis is a subject of further studies.https://www.gastro-j.ru/jour/article/view/238lactobacillus reuteriпробиотикметабиотикhelicobacter pylori |
| spellingShingle | V. T. Ivashkin O. P. Alekseyeva A. Yu. Baranovsky Ye. K. Baranskaya Ye. V. Beloborodova T. A. Kolesov N. V. Korochanskaya K. . Lang T. L. Lapina I. V. Mayev M. V. Mokshina D. L. Nepomnyashchy Ye. V. Onuchina R. G. Sayfutdinov T. H. Sviridova V. I. Simanenkov A. V. Tkachev A. S. Trukhmanov L. P. Faizova I. B. Khlynov O. B. Khlynova A. A. Sheptulin The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) Российский журнал гастроэнтерологии, гепатологии, колопроктологии lactobacillus reuteri пробиотик метабиотик helicobacter pylori |
| title | The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) |
| title_full | The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) |
| title_fullStr | The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) |
| title_full_unstemmed | The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) |
| title_short | The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) |
| title_sort | role of lactobacillus reuteri dsmz17648 for helicobacter pylori eradication therapy review of literature and advisory council resolution february 28 2018 |
| topic | lactobacillus reuteri пробиотик метабиотик helicobacter pylori |
| url | https://www.gastro-j.ru/jour/article/view/238 |
| work_keys_str_mv | AT vtivashkin theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT opalekseyeva theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT ayubaranovsky theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT yekbaranskaya theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT yevbeloborodova theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT takolesov theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT nvkorochanskaya theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT klang theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT tllapina theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT ivmayev theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT mvmokshina theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT dlnepomnyashchy theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT yevonuchina theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT rgsayfutdinov theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT thsviridova theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT visimanenkov theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT avtkachev theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT astrukhmanov theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT lpfaizova theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT ibkhlynov theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT obkhlynova theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT aasheptulin theroleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT vtivashkin roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT opalekseyeva roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT ayubaranovsky roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT yekbaranskaya roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT yevbeloborodova roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT takolesov roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT nvkorochanskaya roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT klang roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT tllapina roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT ivmayev roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT mvmokshina roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT dlnepomnyashchy roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT yevonuchina roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT rgsayfutdinov roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT thsviridova roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT visimanenkov roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT avtkachev roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT astrukhmanov roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT lpfaizova roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT ibkhlynov roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT obkhlynova roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 AT aasheptulin roleoflactobacillusreuteridsmz17648forhelicobacterpylorieradicationtherapyreviewofliteratureandadvisorycouncilresolutionfebruary282018 |