Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy

Thyroid associated ophthalmopathy (TAO) is an autoimmune orbital disease associated with thyroid dysfunction, which may significantly impact the appearance and quality of life of patients. The course of TAO includes active stage and inactive stage, and the treatment methods are different in differen...

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Main Authors: Yan Song, Tuo Li, Wei Tang, Qian Lv, Xing-xing Zhang, Wei-yi Zhou, Yong-quan Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1537957/full
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author Yan Song
Tuo Li
Wei Tang
Qian Lv
Xing-xing Zhang
Wei-yi Zhou
Yong-quan Shi
author_facet Yan Song
Tuo Li
Wei Tang
Qian Lv
Xing-xing Zhang
Wei-yi Zhou
Yong-quan Shi
author_sort Yan Song
collection DOAJ
description Thyroid associated ophthalmopathy (TAO) is an autoimmune orbital disease associated with thyroid dysfunction, which may significantly impact the appearance and quality of life of patients. The course of TAO includes active stage and inactive stage, and the treatment methods are different in different stages. The clinical activity score is often used to evaluate the activity of TAO, but it is easy to be affected by subjective factors because it is based on the symptoms and signs of patients. Magnetic resonance imaging (MRI) can evaluate the postorbital tissue structure of TAO more objectively and accurately. A variety of MRI modalities have been used in the diagnosis and treatment of TAO. This article mainly summarizes the application of MRI in diagnosing TAO, assessing its activity, predicting treatment efficacy, and evaluating therapeutic outcomes, thereby providing clinicians with additional evidence-based options.
format Article
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institution OA Journals
issn 1664-2392
language English
publishDate 2025-06-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Endocrinology
spelling doaj-art-c4629798521341a787e5efef42c7d01d2025-08-20T02:22:01ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-06-011610.3389/fendo.2025.15379571537957Application progress of magnetic resonance imaging in thyroid associated ophthalmopathyYan SongTuo LiWei TangQian LvXing-xing ZhangWei-yi ZhouYong-quan ShiThyroid associated ophthalmopathy (TAO) is an autoimmune orbital disease associated with thyroid dysfunction, which may significantly impact the appearance and quality of life of patients. The course of TAO includes active stage and inactive stage, and the treatment methods are different in different stages. The clinical activity score is often used to evaluate the activity of TAO, but it is easy to be affected by subjective factors because it is based on the symptoms and signs of patients. Magnetic resonance imaging (MRI) can evaluate the postorbital tissue structure of TAO more objectively and accurately. A variety of MRI modalities have been used in the diagnosis and treatment of TAO. This article mainly summarizes the application of MRI in diagnosing TAO, assessing its activity, predicting treatment efficacy, and evaluating therapeutic outcomes, thereby providing clinicians with additional evidence-based options.https://www.frontiersin.org/articles/10.3389/fendo.2025.1537957/fullthyroid associated ophthalmopathymagnetic resonance imagingsignal intensity ratioT2 mappingdiffusion-weighted imaging
spellingShingle Yan Song
Tuo Li
Wei Tang
Qian Lv
Xing-xing Zhang
Wei-yi Zhou
Yong-quan Shi
Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
Frontiers in Endocrinology
thyroid associated ophthalmopathy
magnetic resonance imaging
signal intensity ratio
T2 mapping
diffusion-weighted imaging
title Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
title_full Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
title_fullStr Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
title_full_unstemmed Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
title_short Application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
title_sort application progress of magnetic resonance imaging in thyroid associated ophthalmopathy
topic thyroid associated ophthalmopathy
magnetic resonance imaging
signal intensity ratio
T2 mapping
diffusion-weighted imaging
url https://www.frontiersin.org/articles/10.3389/fendo.2025.1537957/full
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